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The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Leydig cells can cause testosterone-secreting adrenal tumors in women.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

The study concluded that androstendione and DHEA are important for diagnosing high male hormone levels in women with excessive hair growth.

A rare ovarian tumor caused high testosterone, hair loss, and missed periods, but surgery fixed these issues and led to pregnancy.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

The document covers various male health issues, their causes, treatments, and related conditions.

Androgen use may increase the risk of stroke, but more research is needed.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

New treatments for male hypogonadism are effective and should be personalized.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.

Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.

Men with more severe hair loss had a lower risk of schizophrenia, but hair loss and testosterone levels were not linked.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.