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People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

SHBG may be a useful early indicator and treatment target for PCOS.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Suppressing certain hormones might help prevent prostate cancer.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Using stem cells from fat tissue can significantly improve wound healing in dogs.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.