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March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
480 citations,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
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January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
356 citations,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
320 citations,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
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January 2019 in “Pharmaceutics” Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.
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April 2005 in “The New England Journal of Medicine” Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.
225 citations,
July 2007 in “The Journal of Sexual Medicine” Knowing about finasteride's sexual side effects increases reported dysfunction.
198 citations,
October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
153 citations,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
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November 2005 in “Internal Medicine Journal” Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
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July 2012 in “Archives of Dermatological Research” Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
112 citations,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
110 citations,
August 2016 in “Drugs” Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
108 citations,
July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
103 citations,
June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
102 citations,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
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July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
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April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
73 citations,
June 2003 in “Journal of the American Academy of Dermatology” Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.
72 citations,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
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June 2013 in “Journal of feline medicine and surgery” The document says to treat cat fungal infections with medicine and clean the environment, noting that cats without symptoms can still spread it to humans.
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November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
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January 2004 in “Dermatology” Oral finasteride works better than topical minoxidil for hair growth, both are safe.
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April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.