7 citations
,
December 2021 in “Pharmaceutics” This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.
7 citations
,
October 2021 in “Journal of Mind and Medical Sciences” This study found that most milk powder samples tested from the Romanian market contained element concentrations exceeding legal limits, especially potassium, calcium, chlorine, phosphorus, and aluminum.
6 citations
,
January 2020
2 citations
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January 2023 in “Pharmaceuticals” This review discusses factors affecting hair health, types of alopecia, and the potential of phytochemicals in managing hair loss but reports no new clinical results; it highlights the need for further studies.
2 citations
,
January 2023 in “Pharmaceuticals” This study found that in male mice, microglial changes due to a Parkinson's-like lesion were influenced by sex hormones, with dutasteride treatment preventing some effects.
July 2026 in “Pharmaceuticals” This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.
April 2026 in “Cosmetics” In this review, several studies on Astragalus species, particularly Astragalus membranaceus, highlight their skin rejuvenating, photoprotective, antimicrobial, and wound-healing properties, though the authors note limitations due to reliance on non-human studies and short trial durations.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
February 2023 in “Vaccines” This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.
618 citations
,
January 2018 in “Cochrane Database of Systematic Reviews” This study reported that selenium supplements do not reduce cancer risk and may increase the risk of type 2 diabetes and high-grade prostate cancer, while observational studies suggest mixed associations between selenium exposure and cancer incidence.
241 citations
,
January 2001 in “Reviews on Environmental Health” This review discusses the various adverse health effects of chronic selenium exposure in humans, including effects on endocrine and immune function, and suggests current exposure limits may be insufficient.
127 citations
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March 2004 in “Gynecologic oncology” This study concluded that selenium supplementation for ovarian cancer patients during chemotherapy may have several beneficial effects, such as increased antioxidant enzyme activity, reduced chemotherapy-related symptoms, and higher selenium levels in serum and hair.
126 citations
,
November 1987 in “The Journal of Pediatrics” This study reports that selenium deficiency in children on long-term total parenteral nutrition may lead to symptoms like erythrocyte macrocytosis and skin and hair depigmentation, which improved with selenium supplementation.
115 citations
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December 1996 in “PubMed” This study observed that the intestinal absorption of selenium varies depending on its chemical form, with selenomethionine being absorbed efficiently and selenium as selenodiglutathione or selenodicysteine being absorbed faster than selenite.
93 citations
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March 2014 in “Cochrane Database of Systematic Reviews” This review concludes that although observational studies suggest a potential inverse association between selenium exposure and cancer risk, randomized trials show no convincing evidence that selenium supplements prevent cancer in humans and may indicate harmful effects.
79 citations
,
April 1996 in “JAMA” This article describes a case of selenium poisoning in a 36-year-old man who experienced hair loss, nail changes, and paresthesias after taking selenium-containing vitamin tablets.
71 citations
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June 2008 in “Annals of Internal Medicine” This article describes a case of selenosis linked to excessive selenium in a nutritional supplement that led to a product recall due to toxicity concerns.
61 citations
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May 2010 in “Integrative Cancer Therapies” This review discusses the potential benefits and risks of selenium in cancer prevention and treatment, emphasizing that while selenium may offer advantages for tumor patients, further research is needed due to mixed findings regarding diabetes risk.
55 citations
,
February 1990 in “Journal of Nutrition” This study observed that selenium retention in rat hair and nails was influenced by the chemical form of dietary selenium and methionine status, suggesting caution when using these tissues to assess selenium status.
49 citations
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February 2020 in “Scientific reports” In this study, the Selenium-Chitosan-Mupirocin nanohybrid system significantly enhanced wound healing in a rat model of diabetic wound infection compared to the control, suggesting potential for treating mild diabetic wounds.
35 citations
,
January 2001 in “Journal of Animal Science” This study found that dietary selenium levels above 5 ppm can lead to selenosis in pigs, with white-haired pigs showing alopecia sooner than dark-haired pigs.
35 citations
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April 1956 in “Journal of the American Medical Association” This study found that using selenium sulfide shampoo for seborrheic dermatitis was associated with hair loss, which ceased after discontinuing the shampoo.
30 citations
,
January 2023 in “EFSA journal” This review establishes a tolerable upper intake level of 255 μg/day for selenium in adults, warning that supplements and Brazil nuts may cause excess intake.
30 citations
,
September 2016 in “Aging Cell” This study found that selenium deficiency in mice accelerated age-related conditions and metabolic decline but unexpectedly promoted longevity, suggesting low selenium levels might separate healthspan and lifespan.
23 citations
,
August 1989 in “American Journal of Veterinary Research” In this study, high selenium diets from different sources caused weight and hair loss in pigs, with additional hoof and coronary band problems particularly in those fed sodium selenate.
22 citations
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August 2019 in “Environmental research” This study found that the Pseudomonas sp. T5-6-I strain significantly increased selenium accumulation and root hair density in Brassica oleracea, highlighting its potential for phytoremediation and biofortification.
21 citations
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June 1991 in “Journal of Inherited Metabolic Disease” This case report observed that a selenium-deficient diet in a child with propionic acidaemia led to macrocytosis and hair abnormalities, which improved with selenium supplementation.
20 citations
,
February 2013 in “Nutrition” This article reviews the role of prebiotics and the potential of green tea and selenium as alternatives due to their non-toxic nature, but it reports no new research findings.
20 citations
,
August 1960 in “PubMed” This study investigated the effects of selenium sulfide suspension on hair roots after noticing higher abnormal hair root proportions in individuals using the preparation.
18 citations
,
September 2011 in “Livestock science” This study found that maternal Nano-Se supplementation in cashmere goats improved antioxidant status and promoted secondary hair follicle development in fetuses at 110 days.