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The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Certain drugs that block specific enzymes can help treat prostate diseases.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Treat pattern hair loss with finasteride and topical minoxidil.