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    Glossary Sebaceous Gland Hyperplasia

    enlarged oil glands causing small, yellowish facial bumps

    Sebaceous Gland Hyperplasia is a condition where the sebaceous glands, which are responsible for producing oil (sebum) to lubricate the skin, become enlarged. This often results in small, yellowish bumps on the skin, typically on the face. While generally harmless, it can be mistaken for other skin conditions, and its appearance may be of cosmetic concern.

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    1. Next-generation Sequencing Identified a Novel EDA Mutation in a Chinese Pedigree of Hypohidrotic Ectodermal Dysplasia with Hyperplasia of the Sebaceous Glands Acta dermato-venereologica · 2017 · 4 citations
    2. 919 Overexpression of cyclooxygenase-2 in the skin of adult transgenic mice leads to sebaceous gland hyperplasia and thinning of hair shafts Journal of Investigative Dermatology · 2019
    3. Loss of epidermal PLCg1 induced sebaceous gland hyperplasia and sparse hair Journal of dermatological science · 2017
    4. 332 Generation of a gene expression signature for sebaceous glands by transcriptome comparison of psoriasis and sebaceous hyperplasia 2016
    5. Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis 2014 · 42 citations
    6. An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands Dermatologic Therapy · 2021 · 7 citations
    7. Sebaceous gland diseases: clinical picture risk factors and treatment International Journal of Community Medicine and Public Health · 2023
    8. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019 · 181 citations
    9. Aging in the sebaceous gland Frontiers in Cell and Developmental Biology · 2022 · 36 citations
    10. New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice Current pharmaceutical biotechnology · 2012 · 16 citations
    11. 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation Journal of Investigative Dermatology · 2023
    12. Sebaceous glands changes following topical application of citral Acta Dermato Venereologica · 1983 · 14 citations
    13. Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin Journal of Endocrinology · 2000 · 11 citations
    14. Characteristic analysis of sebaceous nevus using dermoscopy and reflectance confocal microscopy Chinese Journal of Dermatology · 2018 · 2 citations
    15. Study regarding the microscopic aspects of pilo-sebaceous units after antiandrogen treatment in hirsute women. PubMed · 2015
    16. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing theneu oncogene under the control of the bovine keratin 5 promoter Molecular Carcinogenesis · 1998 · 47 citations
    17. Nevus Sebaceous Indian Journal of Dermatopathology and Diagnostic Dermatology · 2025
    18. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000 · 179 citations
    19. Iperplasia Collaterale Nella Oncogenesi Sperimentale Del Ratto: Rilievi in corso di trattamento con Vitamina A Tumori Journal · 1961
    20. Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Proceedings of the National Academy of Sciences · 2001 · 201 citations
    21. Phospholipase C 1 is required for skin stem cell lineage commitment The EMBO Journal · 2003 · 101 citations
    22. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice EMBO molecular medicine · 2014 · 81 citations
    23. Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity Cancer Research · 2006 · 70 citations
    24. Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in nackt Mice, a Cathepsin L-Deficient Mutation American Journal Of Pathology · 2002 · 57 citations
    25. Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia upon Cyclooxygenase-2 Overexpression Journal of Investigative Dermatology · 2003 · 41 citations
    26. Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches Medical Science Monitor · 2024 · 18 citations
    27. Diagnosis of common, benign neonatal dermatoses Clinics in Dermatology · 2003 · 7 citations
    28. Dynamic evaluation of pathological changes in a mouse acne model by optical imaging technology Experimental dermatology · 2023 · 2 citations
    29. To study the prevalence of cutaneous manifestationsin newborns and its correlation with defined maternal and neonatal factors International Journal of Medical Research and Review · 2016 · 2 citations
    30. Congenital Hypotrichosis in Japanese White Strain (JW-NIBS) Rabbits. Journal of Toxicologic Pathology · 2000 · 2 citations