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The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Notch signalling helps skin cells differentiate and prevents tumors.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

A20 protein is crucial for normal skin and hair development.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Cultured epithelium can form hair follicles when combined with dermal papillae.

Hair follicle cells can help heal wounds and study skin diseases.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

Tissue from dog stem cells helped grow hair in mice.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Mutant mice help researchers understand hair growth and related genetic factors.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.