September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
15 citations,
January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
April 2019 in “Journal of Investigative Dermatology” Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
24 citations,
July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
January 2012 in “Springer eBooks” The skin has different types of stem cells that can repair and regenerate tissue.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse skin glands need healthy nerves to grow properly during hair growth phases.
5 citations,
February 2015 in “Journal of Comparative Pathology” High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.
42 citations,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
14 citations,
July 2015 in “Journal of Cosmetic Dermatology” Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
7 citations,
February 2021 in “Dermatologic Therapy” Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.
6 citations,
August 2014 in “Toxicologic pathology” Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
30 citations,
April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
13 citations,
December 2020 in “Dermatologic Therapy” Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
463 citations,
September 2004 in “Clinics in dermatology” Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.
November 2022 in “Journal of Investigative Dermatology” Deleting MPZL3 increases skin oil production and reduces body fat.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MPZL3 protein helps keep sebaceous gland size and cell growth in check.
31 citations,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
241 citations,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Dandruff and seborrheic dermatitis are caused by yeast feeding on scalp oils, leading to irritation and flaking.
23 citations,
February 2015 in “The American journal of pathology” Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
September 2023 in “International Journal of Community Medicine and Public Health” Different sebaceous gland diseases can be treated with medications, hormone therapy, or surgical methods.
44 citations,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
73 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
8 citations,
March 2009 in “Differentiation” Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.