Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.

This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.

This study found that Cidea is critical for regulating lipid storage and sebum secretion in sebaceous glands, with its deficiency causing hair issues and impaired skin functions in mice.

This review discusses recent advancements in engineering sebaceous gland organoids for potential regenerative applications, highlighting strategies to create functionalized organoids but reports no new clinical results.

This study explored recent advancements in 3D bioprinting for head and neck defects, highlighting how bioinks and scaffolds may improve treatment customization and functionality by mimicking native tissue features. The research also examined challenges like biocompatibility and regulatory requirements on the path to clinical use.

This study found that sebaceous-gland-derived glycerol significantly contributes to stratum corneum hydration in mice with sebaceous gland deficiencies.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Hair follicles grow hair and release it through the skin.

This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.

This study suggests that TGF-alpha may function in an autocrine or juxtacrine manner rather than promoting cell proliferation during hair growth cycles in ferrets and sheep.

This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.

This article argues that prolactin may have a role in sebaceous gland function and suggests it could be a potential target for treating skin conditions, but reports no new clinical findings.

This study describes a protocol for generating a fully functional 3D integumentary organ system from murine induced pluripotent stem cells, including the formation of hair follicles and sebaceous glands that function in vivo.

In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.

This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.

This study found that acid and alkaline phosphatases serve different functions in Beagle dog skin, with ALP primarily involved in growth processes and ACP in phospholipid breakdown.

This study observed that skin dryness does not seem to indicate impaired epidermal barrier function, as there was no negative correlation between stratum corneum water content and transepidermal water loss.

This study reports that the asebia-2J mutation in mice affects sebaceous gland function and leads to hair follicle destruction, offering a model for human scarring alopecias.

This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.

This study found that rat whisker follicle stem cells can be expanded in culture and transplanted to form functional hair follicles, demonstrating their multipotency and potential for regenerative medicine.

This study reported that using condensed nanofat combined with fat grafts significantly improved the aesthetic and functional aspects of atrophic facial scars in 20 patients, as assessed by both patients and plastic surgeons using the Patient and Observer Scar Assessment Scale.

This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.

This review highlights the impact of obesity on skin health, detailing how it alters skin barrier function, exacerbates conditions like Psoriasis, and is linked to various skin complications without reporting new clinical results.

In this study, rat primary thymic epithelial cells demonstrated a clonogenic growth pattern in vitro and were able to integrate into functional thymus or differentiate into skin derivatives, similar to skin multipotent stem cells.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

In this study, researchers observed that human sebaceous glands can regenerate in a mouse model using transplanted human skin, potentially offering a tool to study sebaceous gland biology and regeneration.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.

This study demonstrates that c-MYC overexpression in sebaceous glands affects differentiation via a regulatory axis involving the androgen receptor and p53, influencing carcinoma formation outcomes.