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This study found that Runx1 in hair follicle stem cells modulates lipid metabolism, impacting membrane organization and enhancing signal transduction for cell proliferation in both normal and cancer epithelial cells.

An artificial lipid barrier can restore hair growth in cases of SCD1 deficiency.

This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

This study found that fatty acid desaturation regulated by SCD1 is crucial for hair growth by maintaining hair follicle stem cell niches, with its absence causing abnormal hair growth in mice.

This study presents evidence that hair matrix progenitors and the enzyme Stearoyl CoA Desaturase 1 may play a role in maintaining the dermal papilla niche via autocrine Wnt and paracrine Hedgehog signaling in mice.

This study reports that the asebia-2J mutation in mice affects sebaceous gland function and leads to hair follicle destruction, offering a model for human scarring alopecias.

In this study, targeted deletion of the stearoyl-CoA desaturase 1 gene in mice disrupted the epidermal lipid barrier, leading to increased water loss, impaired thermoregulation, and metabolic issues.

This review discusses the role of the enzyme Δ9-desaturase-1 in skin lipid regulation and whole-body energy balance in mice and reports no new experimental results.

This review highlights recent findings on the importance of signalling pathways in sebaceous gland morphogenesis and differentiation, but reports no new clinical results.

In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.

New acne treatments show promise as alternatives to traditional therapies.

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.

In this study, researchers observed that TCDD exposure in mice enhanced sebaceous gland differentiation and lipid production before causing seboatrophy, providing insights into the cellular events that may contribute to chloracne pathogenesis.

This study reviews progress in understanding how redesigned lipid metabolism supports energy production and treatment resistance in advanced carcinomas, highlighting a hypothesis supported by preclinical and clinical evidence and suggesting potential clinical targeting of resistance mechanisms.

In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.

This study suggests that a low daily dose of finasteride may be effective in reducing recurrent priapism episodes in children and adolescents with sickle cell disease, though larger controlled studies are needed to confirm these findings.

In this study, the researchers found that constitutive activation of the EGFR in mice led to increased sebum production, enlarged sebaceous glands, and altered gene expression related to sebocyte proliferation and lipogenesis.

This study examined the effectiveness of using intradermotherapy, with or without microneedling and topical solutions, in reducing hair loss among men with androgenetic alopecia, though results are not reported in the abstract.

This report describes a 17-year-old woman who experienced severe anagen effluvium after DRESS syndrome but achieved full recovery in two months with topical minoxidil.

In this study, complete recovery from folliculitis dissecans was observed after intradermal botulinum toxin A injections, with the effect attributed to the host response rather than direct bacterial action.

This article examines the potential of using oral minoxidil as an adjuvant treatment for patients with severe alopecia areata who do not respond to increased doses of Janus kinase inhibitors, but provides no new clinical results.

In this animal study, a topical gel containing ethyl-methyl-hydroxypyridine succinate showed potential in accelerating hair regrowth and improving skin biochemical parameters in rats with chemically induced alopecia, suggesting its possible benefit for alopecia related to oxidative stress.

This article reviews temporal triangular alopecia, emphasizing the utility of dermoscopy for diagnosis, and reports no new clinical treatment findings.

This report discusses a 48-year-old patient with androgenetic alopecia and basal cell carcinoma on the right hairline, where forehead reduction surgery and tumor excision were performed simultaneously, improving aesthetics and resolving the cancer issue.

This article reviews a case of alopecia triangularis temporalis, emphasizing the need for histopathological confirmation to avoid misdiagnosis and highlighting surgical correction as the preferred treatment for confirmed cases.

In this case study, a 35-year-old man with recalcitrant folliculitis decalvans was successfully treated with Erbium-YAG laser, showing rapid improvement without hair loss, though further clinical studies are needed to define its benefits more comprehensively.