January 2024 in “Surgical & Cosmetic Dermatology” This source describes two cases of hair transplantation in transgender patients with Androgenetic Alopecia, showing good results using Follicular Unit Extraction and Follicular Unit Transplantation techniques, highlighting the need for more research specific to this population.
January 2024 in “Surgical & Cosmetic Dermatology” This review discusses recent research on exosomes' role in dermatology, highlighting their involvement in skin diseases and rejuvenation and exploring therapeutic possibilities in these areas.
January 2024 in “Surgical & Cosmetic Dermatology” In this article, the researchers emphasized the importance of proper incision angles and careful preparation of the receiving site during eyebrow hair transplants to achieve natural-looking results, highlighting that meticulous planning in design and positioning is crucial.
January 2022 in “Surgical & Cosmetic Dermatology” This case report described a rare instance of new curly hair growth in a patient undergoing isotretinoin treatment for acne vulgaris, highlighting the potential for isotretinoin to alter hair fiber curvature.
January 2022 in “Surgical & Cosmetic Dermatology” This review concludes that the two-stage technique of hair transplantation with prior fat grafting appears effective for treating scalp scars, based on existing literature.
January 2020 in “Surgical and Cosmetic Dermatology” This study found that a topical hair ampoule containing human follicle stem cells significantly improved hair growth and scalp coverage in women with androgenetic alopecia after four months of use.
January 2018 in “Surgical and Cosmetic Dermatology” This review provides an in-depth examination of the efficacy and safety of finasteride and dutasteride, commonly used for treating benign prostatic hyperplasia and male androgenetic alopecia.
January 2018 in “Surgical and Cosmetic Dermatology” In this study, researchers validated a software-based method that quantitatively assesses the effectiveness of treatments for hair loss by calculating the area of hair loss using contrast in standardized photographs, proving effective for both early and advanced cases of androgenetic alopecia and telogen effluvium.
January 2018 in “Surgical and Cosmetic Dermatology” This study found that a nutraceutical containing vitamins and trace elements was effective in reducing telogen strands and improving hair and nail conditions in individuals with telogen effluvium and brittle nails syndrome.
January 2022 in “Surgical and Cosmetic Dermatology” This study found a significant correlation between androgenic alopecia and metabolic syndrome, suggesting individuals with alopecia have higher odds of metabolic syndrome.
January 2022 in “Surgical and Cosmetic Dermatology” This case report of a 37-year-old woman with female pattern alopecia found no significant histopathological changes or follicle count improvement after three sessions of scalp microneedling.
January 2017 in “Surgical and Cosmetic Dermatology” This study reported that combining Erbium Glass 1550nm laser therapy with scalp injections of minoxidil, finasteride, growth factors, and vitamins was an effective and safe treatment for androgenetic alopecia, with 96.77% of participants expressing satisfaction, especially those who underwent more than six sessions.
January 2015 in “Surgical and Cosmetic Dermatology” This study found that platelet-rich plasma injections may lead to improved hair growth and follicle health in individuals with androgenic alopecia, showing a higher average improvement in women compared to men.
6 citations
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September 2019 in “Journal of cosmetic dermatology” This study found that lower serum melatonin levels were associated with increased skin aging grades among individuals in Ulaanbaatar, suggesting melatonin loss may contribute to earlier skin aging.
3 citations
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December 2018 in “International Journal of Biomedicine” This study found that treating androgenetic alopecia with platelet rich plasma increased hair density and diameter while decreasing the proportion of telogen and vellus hairs.
33 citations
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March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
January 2016 in “Surgical and Cosmetic Dermatology” This study showed that platelet-rich plasma treatment led to a statistically significant increase in terminal hairs and a reduction in vellus hairs in men with androgenetic alopecia.
January 2015 in “Surgical and Cosmetic Dermatology” This study reported effective hair growth improvement in androgenic alopecia through subcutaneous injections of platelet-rich plasma, with observed benefits in both women and men.
19 citations
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July 2015 in “Journal of inherited metabolic disease” This study observed that while betaine supplementation decreases total homocysteine and increases methionine levels in a mouse model of CBS deficiency, it is not as effective as methionine restriction in reversing associated phenotypes.
11 citations
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December 2013 in “Clinical and experimental dermatology” This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.
499 citations
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September 2011 in “Cell” This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.
437 citations
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August 2014 in “Cell metabolism” This perspective suggests that browning agents may not directly enhance UCP1 expression in white adipose tissue but instead induce browning through increased heat loss, prompting thermogenesis to compensate.
236 citations
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July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
205 citations
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April 2005 in “Journal of Investigative Dermatology” This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.
173 citations
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January 2014 in “Nature Cell Biology” This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.
150 citations
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October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
146 citations
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May 2002 in “The American journal of pathology” This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.
137 citations
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September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” In this study, researchers found that transgenic expression of the Hairless gene in keratinocytes can restore hair follicle regeneration in Hr-deficient mice by repressing Wise, a modulator of Wnt signaling.
134 citations
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January 2011 in “Development” This study found that disrupting Adam10 in the epidermis led to severe skin and multi-organ abnormalities, implicating Adam10 as crucial for proper Notch signaling and skin maintenance.