8 citations
,
November 2024 in “EMBO Molecular Medicine” In this study, researchers found that disrupting EGFR signaling in mice led to increased inflammation and hair follicle damage but that inhibiting the JAK-STAT1 pathway could restore hair growth and skin function.
8 citations
,
January 2008 in “PubMed” This study reports that mesotherapy can lead to serious complications, such as multifocal scalp abscesses and subcutaneous fat necrosis, requiring extensive surgical repair.
6 citations
,
January 2023 in “npj regenerative medicine” This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.
6 citations
,
March 2018 in “Proceedings - Baylor University. Medical Center” This case report describes a patient with sarcoidosis who experienced severe symptomatic hypercalcemia, scarring alopecia, and acute-on-chronic kidney failure.
6 citations
,
May 2013 in “Journal of Clinical Oncology” Combining Ficlatuzumab and Gefitinib can cause severe hair loss.
6 citations
,
January 2013 in “Journal of Cosmetics Dermatological Sciences and Applications” This study found that lichen planopilaris is a common cause of scalp scarring alopecia in adults and has distinctive clinical features that help differentiate it from other similar conditions.
5 citations
,
April 2024 in “BMJ Open” This scoping review revealed that methods for measuring traumatic scar thickness using ultrasound are inconsistently reported and mainly remain in early research phases, highlighting a need for standardizing these methods to bridge the gap to routine clinical practice.
5 citations
,
September 2023 in “Journal of Cosmetic Dermatology” This study found that c-Maf positive M2 macrophages may promote hypertrophic scar formation by enhancing the proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts through increased TGF-β1 expression.
5 citations
,
August 2022 in “Mediators of Inflammation” This study found that combining pulsed dye laser with pingyangmycin improved treatment efficacy, scar repair, skin condition, and patient satisfaction in treating post-acne hyperplastic scars, compared to laser alone, without increasing adverse reactions.
5 citations
,
February 2017 in “Facial Plastic Surgery Clinics of North America” Improve chin and perioral scars with surgery, resurfacing, and other therapies, tailored to each patient.
5 citations
,
November 2023 in “Journal of Investigative Dermatology” This study observed that cutaneous microwounds created by fractional photothermolysis heal differently from typical wounds, displaying rapid re-epithelialization and limited inflammation, which may help reduce scar formation by delaying collagen remodeling and minimizing myofibroblast activation.
5 citations
,
March 2017 in “Journal of the American Academy of Dermatology” Cytokeratin-15 loss is not specific to any single type of scarring alopecia.
5 citations
,
February 2017 in “Australasian Journal of Dermatology” This report describes three cases of hair loss that appear consistent with cicatricial pattern hair loss, a possible new subtype of scarring alopecia presenting in a female pattern hair loss distribution.
4 citations
,
November 2024 in “International Journal of Biological Macromolecules” In this study, the researchers developed a cellulose nanofiber-based scaffold containing sitagliptin and zinc sulfide nanoparticles, which promoted scarless healing and hair follicle regeneration in rats by targeting DPP4+ fibroblasts, suggesting a novel approach for improved wound healing and skin regeneration.
4 citations
,
July 2023 in “Experimental Dermatology” This study found that incorporating human adipose subcutaneous tissue in 3D organotypic skin cultures mimicking hypertrophic scar conditions improved epidermal homeostasis, formed a basement membrane similar to native skin, and reduced myofibroblast presence, indicating an anti-fibrotic effect.
4 citations
,
September 2024 in “Cell Reports” This study found that mice lacking the CXCR2 receptor regenerated tissue scarlessly in various injury models and that administering plasma or G-CSF from these mice to wild-type mice also reduced scarring, suggesting potential therapeutic strategies to improve human skin wound healing.
4 citations
,
November 2021 in “Biomedicines” This review discusses the challenges in diagnosing primary cicatricial alopecias and explores how improved communication and digital pathology could enhance diagnosis, but it reports no new clinical results.
4 citations
,
January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
4 citations
,
November 2016 in “Journal of Cutaneous Pathology” This letter discusses three plasmacytoid dendritic cell-related parameters that may help differentiate lupus alopecia from lichen planopilaris, but it reports no new study results.
4 citations
,
July 2015 in “Case Reports in Dermatology” This article describes a rare case of syringomas on the scalp in a 56-year-old woman with alopecia, highlighting the importance of scalp biopsy for diagnosing atypical neoplastic lesions and associated conditions.
3 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” This study using a mouse model reports that CuATSM treatment accelerates skin wound healing and reduces scar formation, with effects possibly mediated via the ferroptosis-induced Hippo/YAP signaling pathway and macrophage polarization, suggesting CuATSM as a potential therapy for scarless wound healing in clinical settings.
3 citations
,
June 2020 in “Dermatologic Surgery” This study found that dense-packing megasession follicular unit extraction is a safe and effective method for treating extensive scarring alopecia, with a graft survival rate of 85% and high patient satisfaction.
3 citations
,
March 2019 in “Archives of Plastic Surgery” This study found that hair transplantation effectively corrected altered hairlines and scarring arising from midface-lifting surgery, achieving high patient and physician satisfaction scores without adverse events.
3 citations
,
November 2017 in “The American Journal of Cosmetic Surgery” This study evaluated donor area scars in hair restoration using a new assessment scale and found that most patients had good quality scars, with average scores of 15 or less out of 40.
3 citations
,
January 2009 in “Medical Hypotheses” This study reports that topical iodine can initiate, control, and complete the regeneration of human scar tissue, with hair playing a key role in the process.
3 citations
,
June 2025 in “Archives of Dermatological Research” In this review, researchers found that TNF-α, IL-17, and JAK inhibitors show the most promise for stabilizing and resolving scarring alopecias, with IL-23 and Interferon Alpha Receptor 1 inhibitors also providing some benefits in managing these hair loss conditions.
3 citations
,
January 2010 in “Journal of The European Academy of Dermatology and Venereology” This article provides no abstract or new research findings on the androgenic pattern presentation of scarring and inflammatory alopecia.
3 citations
,
January 2025 in “SAGE Open Medical Case Reports” In this case report, a 48-year-old woman with refractory discoid lupus erythematosus showed significant improvement, including hair regrowth, after treatment with deucravacitinib, suggesting its potential as an effective therapy for this condition.
3 citations
,
August 2024 in “Skin Research and Technology” In this study, LC-OCT imaging was found to noninvasively identify specific features of cicatricial alopecia due to lupus erythematosus, such as hyperreflective collagen fibers, which may aid in distinguishing it from other types of scarring alopecia.
3 citations
,
March 2022 in “PubMed” This review discusses the use of platelet-rich plasma in treating various forms of alopecia, including androgenic alopecia and alopecia areata, but provides no new clinical results.