17 citations
,
August 2024 in “International Journal of Biological Macromolecules” The hydrogel dressings speed up healing and reduce scarring.
17 citations
,
May 2016 in “Archives of Dermatological Research” This study identified specific reflectance confocal microscopy features that help differentiate scarring from non-scarring alopecia, providing a non-invasive diagnostic tool.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
17 citations
,
January 2020 in “Skin appendage disorders” This review suggests that the Mediterranean diet, protein-rich diets, and soy may support hair health in nonscarring alopecias like androgenetic alopecia.
16 citations
,
December 2016 in “Dermatologic Surgery” This study observed that donor strip scar width after hair transplantation was correlated with preoperative scalp laxity and elasticity but not with glidability.
14 citations
,
December 2013 in “Anais Brasileiros De Dermatologia” This case report describes a young Brazilian woman with scalp psoriasis that progressed to the rare complication of scarring alopecia.
14 citations
,
July 1994 in “Journal of Dermatological Science” In this study, transgenic mice expressing a mutant K6 gene developed progressive scarring alopecia and keratosis, suggesting they may model a new keratin disorder.
13 citations
,
March 1998 in “Journal of Biomedical Materials Research” This study found that island grafting in guinea pigs enabled the isolated study of early skin regeneration processes, distinguishing them from natural wound closure mechanisms like epithelialization and contraction.
13 citations
,
April 2025 in “International Journal of Nanomedicine” In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.
13 citations
,
January 2020 in “Scientific Reports” This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.
13 citations
,
January 2022 in “Stem cell reviews and reports” This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.
13 citations
,
March 2011 in “British Journal of Dermatology” This report describes a case of primary cutaneous follicle centre cell lymphoma presenting as hair thinning on the scalp, which is not a recognized feature of the condition.
13 citations
,
April 2001 in “International Journal of Dermatology” Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
11 citations
,
May 2019 in “BioMed Research International” The researchers reported that follicular unit hair transplantation achieved a mean graft survival rate of 80.67% and significantly improved patient and observer satisfaction in individuals with stable cicatricial alopecia from postsurgical scalp scarring.
11 citations
,
January 1988 in “PubMed” This study found that epidermal cell extract from keratinocytes may promote epidermal cell proliferation and migration while inhibiting fibroblast activity, potentially reducing scarring in wound healing.
11 citations
,
August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
11 citations
,
January 2012 in “Archives of Dermatology” Polarized microscopy is a quick and free method to correctly identify types of hair loss.
11 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
11 citations
,
May 2011 in “Journal of Cutaneous Medicine and Surgery” This report describes a case of lichen planopilaris potentially triggered by chronic scalp trauma from break dancing, emphasizing the need for careful examination to differentiate it from androgenetic alopecia.
10 citations
,
January 2015 in “European journal of pharmacology” In this animal study, ginsenoside Rb1 demonstrated therapeutic effects on hypertrophic scar remodeling, with the highest efficacy observed at a dose of 0.56 mg.
10 citations
,
January 2018 in “Organogenesis” This study found that epidermal stem cell-specific Jag1 expression levels are crucial for effective wound healing and scar reduction, and porcine acellular dermal matrix treatment enhances this process in mice by boosting Notch/Jagged1 signaling.
10 citations
,
January 2017 in “Dermato-Endocrinology” This study found that the scarring folliculitis type of acne inversa in the Chinese population is associated with specific histopathological features and a higher prevalence of smoking and occupational exposure.
10 citations
,
June 2015 in “Seminars in cutaneous medicine and surgery” This review discusses the biology of hair follicles and mechanisms behind various hair disorders, but it presents no new findings; the authors emphasize understanding these concepts to inform treatment development.
9 citations
,
November 2015 in “Plastic and reconstructive surgery/PSEF CD journals” This study found that human skin grafted onto certain immunodeficient mice resulted in proliferative scars with characteristics similar to human hypertrophic scars, suggesting these models may better represent the condition's natural history.
9 citations
,
November 2018 in “Drug Discovery Today” This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.
9 citations
,
January 1995 in “Aesthetic Plastic Surgery” This study observed that using a relaxed suture technique on scalp incisions may prevent linear scars by reducing pressure on upper stem cells.
8 citations
,
May 2021 in “Applied Materials Today” This study found that Cur-Fe-mesoporous silica nanoparticles synergistically inhibited scar formation and promoted hair follicle regeneration in skin burn wound healing by releasing bioactive components like SiO32−, Fe3+, and Fe-Cur chelates.
8 citations
,
January 2015 in “Scars, burns & healing” This review discusses surgical and non-surgical options for hair restoration in burn alopecia, highlighting follicular unit extraction and transplant as preferred methods but reports no new clinical findings.
8 citations
,
April 2022 in “Burns” In this study, researchers found that moisturizers like Alhydran and DermaCress provided superior hydration and occlusion compared to silicone gel, suggesting these moisturizers may be a patient-friendly and cost-effective alternative for scar management.
8 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This article reviews methods for managing the donor area in hair restoration surgery to minimize scarring and reports no new results.