9 citations
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June 2025 in “Frontiers in Pharmacology” This review highlights recent advancements in microneedle technology, noting its ability to enhance transdermal drug delivery, biosensing, cancer treatment, and skin disease repair, while emphasizing its potential for improving patient compliance and reducing side effects.
June 2026 in “Journal of Cutaneous and Aesthetic Surgery” This study examined five patients with cicatricial alopecia treated using the follicular unit extraction technique, finding an average graft survival rate of 64.2% and acceptable transection rates, despite the procedure's challenges compared to non-scarring alopecia.
May 2023 in “Antioxidants” In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.
10 citations
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February 2021 in “Pharmaceutics” In this study, the novel fatty acid-conjugated tetrapeptide Palmitoyl-GDPH enhanced wound healing in rats by improving re-epithelialization and collagen deposition with minimal toxicity observed at the used dosage.
May 2026 in “Cell Reports Medicine” This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.
8 citations
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April 2020 in “Facial Plastic Surgery Clinics of North America” This article discusses the advancements in follicular unit transplantation for hair restoration and reports no clinical results; it emphasizes improved aesthetic outcomes using updated techniques.
3 citations
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December 2022 in “Cells” This review examines the role of cannabinoid compounds in treating various skin conditions and suggests their potential as systemic and topical therapies, but it reports no new experimental results.
3 citations
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June 2025 in “Journal of Cellular and Molecular Medicine” This study using a mouse model reports that CuATSM treatment accelerates skin wound healing and reduces scar formation, with effects possibly mediated via the ferroptosis-induced Hippo/YAP signaling pathway and macrophage polarization, suggesting CuATSM as a potential therapy for scarless wound healing in clinical settings.
March 2026 in “Wound Repair and Regeneration” In this study, researchers used a mouse model to demonstrate that expression of MARCKSL1 in dendritic cells plays a crucial role in modulating fibrotic responses and scar formation during wound healing, suggesting that targeting this expression could offer new therapeutic strategies for scar prevention.
August 2024 in “Nature Communications” This study found that in female mice, softer, lightly crosslinked gelatin-based hydrogels promoted better wound healing with less scarring and inflammation compared to stiffer, heavily crosslinked hydrogels, affecting immune and stromal cell behavior.
February 2024 in “Advanced Science” This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.
October 2022 in “IntechOpen eBooks” This source highlights the challenges in treating cicatricial alopecia, noting that follicular unit extraction hair transplantation offers a minimally invasive and successful option to improve cosmetic outcomes for patients with permanent hair loss from scarring.
30 citations
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May 2019 in “Medicinal Research Reviews” This review discusses molecular and cellular strategies to improve muscle and skin regeneration and reduce scarring after cleft lip repair, offering potential benefits for function and aesthetics.
January 2025 in “PLoS ONE” This study found that aligned electrospinning membranes enhance skin wound healing by upregulating MMP12 expression and inhibiting fibroblast migration, which results in reduced scar formation, providing valuable insights for developing more effective biological dressings.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
5 citations
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February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.
March 2024 in “Biomedicines” This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.
74 citations
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August 2023 in “Frontiers in Immunology” In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.
48 citations
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May 2013 in “Canadian Medical Association Journal” This article discusses common causes of hair loss, specifically androgenetic alopecia and alopecia areata, but reports no new clinical findings.
17 citations
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August 2024 in “International Journal of Biological Macromolecules” The hydrogel dressings speed up healing and reduce scarring.
14 citations
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January 2025 in “Biomaterials Research” This review discusses the use of bioactive glass in skin tissue repair and highlights its potential to aid wound healing through effects on inflammatory cells and tissue regeneration, but reports no new experimental findings.
10 citations
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January 2024 in “Burns & Trauma” This meta-analysis found that ADSC-Exo therapy can enhance healing in both general and diabetic wounds by promoting neovascularization, improving epithelization and collagen fiber deposition, and reducing scar formation, suggesting significant potential for clinical and research applications.
5 citations
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January 2025 in “Burns & Trauma” This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.
4 citations
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July 2023 in “Experimental Dermatology” This study found that incorporating human adipose subcutaneous tissue in 3D organotypic skin cultures mimicking hypertrophic scar conditions improved epidermal homeostasis, formed a basement membrane similar to native skin, and reduced myofibroblast presence, indicating an anti-fibrotic effect.
3 citations
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February 2023 in “Journal of Investigative Dermatology” Ch55 may help reduce skin scarring and fibrosis.
2 citations
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July 2024 in “International Journal of Transgender Health” This study reviewed literature on dermatological changes in transgender and gender diverse individuals during gender affirming medical transition, identifying risks like acne and hypertrophic scars, and provided tailored care recommendations for health professionals.
2 citations
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September 2022 in “Cytotherapy” This review summarizes recent research on the therapeutic uses of adipose-derived stem cells for wound healing and treating skin diseases but does not provide new experimental results.
1 citations
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October 2024 in “BMC Pediatrics” In this study, researchers analyzed data from 132 hospitalized kerion patients over 11 years, mostly children under 11 from rural areas, and noted a significant male predominance and frequent animal contact as potential transmission factors.
1 citations
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August 2024 in “European Journal of Medicinal Chemistry Reports” This systematic review examines the landscape of cosmetic microneedling using SWOT analysis, identifying strengths like precise delivery and self-administration, while noting challenges such as potential skin damage and regulatory issues, with opportunities in AI-enhanced targeted treatments noted by these researchers.
January 2024 in “Journal of cosmetic dermatology” This study found that long-hair follicular unit excision for hairline restoration resulted in high patient satisfaction, with a 93% graft survival rate and improved quality of life scores postoperatively.