3 citations
,
August 2012 in “Annals of Diagnostic Pathology” This study found that women with AIDS had significantly reduced epithelial thickness and more telogen hair follicles on the scalp compared to women without AIDS.
45 citations
,
November 2017 in “Biomaterials” This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.
1 citations
,
May 2023 in “Frontiers in medicine” This review explores how hair dyes and perms can damage hair structure and notes that while some adverse outcomes like skin irritation and allergic reactions have been reported, evidence from human studies remains inconsistent regarding potential risks, including cancer.
January 2025 in “International Journal of Pharmacognosy and Clinical Research” This study reported the development of a scalp serum containing Beta-Sitosterol and nutrient-rich oils, showing stable physicochemical properties, suggesting potential for promoting hair growth and scalp health, though further clinical testing in humans is needed to confirm effectiveness.
33 citations
,
January 2002 This study found that daily topical application of 500 microg/ml latanoprost led to moderate to marked hair regrowth in a macaque model of androgenetic alopecia.
5 citations
,
October 1988 in “Clinics in Dermatology” This article reviews various types of alopecia, their diagnostic features, and patterns, but presents no new clinical findings; the authors discuss multiple mechanisms and classification challenges.
89 citations
,
January 2013 in “Acta dermato-venereologica” This review examines dandruff and seborrheic dermatitis, highlighting the role of Malassezia yeasts in inflammation and hyper-proliferation, and reports no new clinical findings.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
100 citations
,
September 1999 in “British Journal of Dermatology” This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.
33 citations
,
June 2017 in “Developmental Biology” This study found that local refinement of hair follicles into higher order patterns can occur without the core planar cell polarity system, but global alignment with body axes requires its function throughout development and regeneration.
68 citations
,
May 2018 in “PLOS Biology” This study demonstrates that inhibiting SFRP1 with the antagonist WAY-316606 enhances hair growth in human scalp hair follicles ex vivo by facilitating Wnt signalling.
November 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This review highlights that practicing Shiroabhyang, an Ayurvedic scalp massage technique using essential oils, may enhance blood circulation, provide nourishment, and improve hair quality by repairing damage and enhancing texture in hair.
33 citations
,
April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
1 citations
,
October 2023 in “International Journal of Women s Health” In this study, scalp hydration and pH levels were not significantly different between hijab-wearing and non-hijab-wearing women, suggesting that hijab-wearing does not impair scalp health if there's no history of underlying scalp or skin disorders and the hijab is not worn damp.
August 2026 in “Skin Research and Technology” This study observed that among individuals with scalp seborrhoea, the scalp showed higher sebum levels, lower hydration, and compromised barrier function compared to other areas, and that a single shampoo application containing piroctone olamine significantly reduced sebum and oxidative stress markers.
May 2026 in “Therapeutic Delivery” This study found that applying a dutasteride-loaded liposome formulation to damp rat skin nearly doubled the drug's follicular accumulation compared to dry skin, suggesting scalp hydration status may significantly impact the drug's topical delivery, especially in follicle-rich areas.
November 2023 in “Global Medical Genetics” This case report describes a 1-month-old male infant with Netherton syndrome, characterized by severe hypernatremia, skin and scalp issues, highlighting the syndrome's complications, including growth retardation and infection risks in early life.
January 2022 in “OPAL (Open@LaTrobe) (La Trobe University)” This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.
211 citations
,
June 2012 This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.
241 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the roles of sebaceous gland activity, Malassezia yeast, and individual susceptibility in scalp flaking disorders, including dandruff and seborrheic dermatitis, but reports no new experiment results.
149 citations
,
September 2017 in “Pharmaceutics” This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.
141 citations
,
September 2016 in “European Journal of Dermatology” This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.
93 citations
,
April 2012 in “International Journal of Cosmetic Science” This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.
73 citations
,
April 2019 in “Experimental Dermatology” This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.
61 citations
,
October 2011 in “Experimental dermatology” This review discusses the neurobiology and proposed mechanisms of scalp itch, but it does not report new clinical findings, highlighting the need for further research in this area.
60 citations
,
January 2014 in “Anais Brasileiros De Dermatologia” This article discusses the foundational concepts of nanotechnology and its contributions to dermatology and medicine, but does not present new research findings.
40 citations
,
January 2018 in “International journal of trichology” This article reviews the relationship between scalp conditions and hair health, suggesting that shampoos with Malassezia inhibitory agents may help reduce premature hair loss, but it presents no new clinical results.
38 citations
,
September 2017 in “Oncologist” This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.
32 citations
,
January 1994 in “Skin Pharmacology and Physiology” In this study, scalp skin from stumptailed macaques demonstrated minoxidil sulfotransferase activity primarily in hair follicles, which may explain minoxidil's hair growth stimulation in this model.