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    Glossary scaffolds

    structures supporting cell growth and tissue formation

    In the context of hair and biology, scaffolds refer to structures made from biocompatible materials that provide a supportive framework for cells to grow and form new tissues. These scaffolds can be used in regenerative medicine to help repair or replace damaged tissues, including hair follicles, by mimicking the natural extracellular matrix and promoting cell adhesion, proliferation, and differentiation.

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    1. Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration Materials Today Bio · 2021 · 22 citations
    2. Immunolocalization of Scaffoldin, a Trichohyalin‐Like Protein, in the Epidermis of the Chicken Embryo The Anatomical Record · 2014 · 17 citations
    3. Application of Scaffold-Based Drug Delivery in Oral Cancer Treatment: A Novel Approach Pharmaceutics · 2024 · 25 citations
    4. Scaffold-Assisted Artificial Hair Implantation in a Rat Model JAMA Facial Plastic Surgery · 2017 · 1 citations
    5. Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design 2024
    6. Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications Journal of Biomaterials Science, Polymer Edition · 2019 · 39 citations
    7. 1619 Spatial transcriptomic analysis of imiquimod-treated mouse skin reveals deregulation of lipid raft-associated markers which could be reversed by re-introduction of caveolin scaffolding domain peptide Journal of Investigative Dermatology · 2023
    8. Maintaining Inducibility of Dermal Follicle Cells on Silk Fibroin/Sodium Alginate Scaffold for Enhanced Hair Follicle Regeneration Biology · 2021 · 7 citations
    9. Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy Stem Cell Research & Therapy · 2020 · 48 citations
    10. Collagen and Fractionated Platelet-Rich Plasma Scaffold for Dermal Regeneration 2016 · 42 citations
    11. Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold Biomolecules · 2020 · 29 citations
    12. Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration Journal of Bionic Engineering · 2021 · 23 citations
    13. Degradation of human hair keratin scaffold implanted for repairing injured skeletal muscles. PubMed · 2002 · 5 citations
    14. Bioabsorbable nano-micelle hybridized hydrogel scaffold prevents postoperative melanoma recurrence Journal of controlled release · 2023 · 4 citations
    15. Promotion of hair growth by a conditioned medium from human umbilical cord mesenchymal stem cells cultivated in a 3D scaffold of gelatin sponge European journal of medical research · 2024 · 2 citations
    16. Feasibility of repairing skin defects by VEGF<sub>165</sub> gene‐modified iPS‐HFSCs seeded on a 3D printed scaffold containing astragalus polysaccharide Journal of Cellular and Molecular Medicine · 2023 · 1 citations
    17. A bio-polymeric scaffold incorporated with p-Coumaric acid enhances diabetic wound healing by modulating MMP-9 and TGF-β3 expression Colloids and surfaces. B, Biointerfaces · 2023 · 1 citations
    18. Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    19. Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights Biomolecules · 2025
    20. Design and initial characterization of fabricated composite scaffold dHPCTM-HPE (decellularized human placental connective tissue matrix - human placental extract) Research Square (Research Square) · 2023
    21. Bilayer Silk Fibroin/Sodium Alginate Scaffold Delivered hUC-MSCs to Enhance Skin Scarless Healing and Hair Follicle Regeneration with the IRE1/XBP1 Pathway Inhibition ACS Biomaterials Science & Engineering · 2023
    22. 883 Hair follicle bulb developed as 3D scaffold free microtissue Journal of Investigative Dermatology · 2017
    23. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity The Journal of Cell Biology · 2015 · 98 citations
    24. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? 2008 · 30 citations
    25. Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute Stem cell research & therapy · 2014 · 45 citations
    26. Ultrasound-activated piezoelectric hydrogel scaffold for synergistic immunomodulation and angiogenesis in accelerated wound healing Acta Biomaterialia · 2025
    27. Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration Biomacromolecules · 2011 · 162 citations
    28. Extracellular matrix‐based combination scaffold for guided regeneration of large‐area full‐thickness rabbit burn wounds upon a single application Journal of biomedical materials research. Part B, Applied biomaterials · 2021 · 3 citations
    29. Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation Photochemical & photobiological sciences · 2014 · 2 citations
    30. A 3D-printed hydrogel scaffold promotes infected diabetic wound repair via anti-inflammation, angiogenesis, and extracellular matrix remodeling Materials & Design · 2026