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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Activating TRPV3 stops human hair growth.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Fullerenes show potential in skin care but need more safety research.

Voriconazole can cause serious side effects, especially in long-term use.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Alopecia areata treatment varies, with no optimal method established yet.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.