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    Glossary SAFE System

    hair transplant technique involving simultaneous follicle extraction and implantation

    The SAFE System is a hair transplant technique that stands for "Simultaneous Harvesting and Follicular Extraction." It involves extracting hair follicles from the donor area and implanting them into the recipient area in a synchronized manner, minimizing the time follicles spend outside the body. This method aims to improve graft survival rates and overall transplant outcomes.

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    1. Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness Molecules · 2020 · 37 citations
    2. Mesenchymal stem cells and their secretome - candidates for safe and effective therapy for systemic lupus erythematosus Medical Journal of Cell Biology · 2021 · 6 citations
    3. Is methotrexate an effective and safe treatment for maintaining hair regrowth in people with alopecia totalis? A Critically Appraised Topic 2018 · 12 citations
    4. ANDROGRAPHOLIDE LOADED TOPICAL NANOCARRIERS FOR MANAGEMENT OF PSORIASIS: A SAFE AND EFFECTIVE APPROACH PLANT ARCHIVES · 2021 · 2 citations
    5. Isolated hyperthermic chemotherapy perfusion for limb melanoma is a safe procedure Journal of Clinical Oncology · 2004
    6. New Methodology and Instrumentation for Follicular Unit Extraction: Lower Follicle Transection Rates and Expanded Patient Candidacy Dermatologic Surgery · 2008 · 30 citations
    7. New Methodology and Instrumentation for Follicular Unit Extraction Dermatologic Surgery · 2006 · 27 citations
    8. Follicular unit extraction Cambridge University Press eBooks · 2009 · 1 citations
    9. COMMENTARY Dermatologic Surgery · 2006 · 1 citations
    10. A Look Back at Hair Restoration through History International journal of transplantation & plastic surgery · 2017
    11. Literature Reviews The American Journal of Cosmetic Surgery · 2006
    12. Hair Growth-Promoting Potential of Semecarpus anacardium: Mechanistic Insights and Pharmacological Evidence Asian Journal of Research in Pharmaceutical Sciences · 2026
    13. HX09 A cut above: the hair-raising history of transplantation British Journal of Dermatology · 2025
    14. A Systematic Review of Case Series and Clinical Trials Investigating Regenerative Medicine for the Treatment of Vitiligo Journal of Cosmetic Dermatology · 2024
    15. International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women Climacteric · 2021 · 9 citations
    16. Systematic review: The platelet-rich plasma use in female androgenetic alopecia as effective autologous treatment of regenerative plastic surgery Journal of Plastic Reconstructive and Aesthetic Surgery · 2021 · 5 citations
    17. Safety of oral JAK inhibitors in treating alopecia areata: a systematic review and network meta-analysis Frontiers in Pharmacology · 2025 · 3 citations
    18. Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Journal of Cutaneous Medicine and Surgery · 2023 · 2 citations
    19. The Scalp as a Donor Site in Pediatric Burns: Systematic Review of the Literature and Proposal of a Management Algorithm European Burn Journal · 2026
    20. Caffeine Supplementation and Hair: A Systematic Review Journal of Drugs in Dermatology · 2025
    21. Efficacy and Safety of Platelet-Rich Plasma Therapy in Alopecia Areata Patients: A Systematic Review Dermatologic Therapy · 2023
    22. Effectiveness of regenerative medicine for skin lightening and rejuvenation: a systematic review of extracellular vesicles and conditioned media Stem Cell Research & Therapy · 2025
    23. Evaluation of the Safety and Effectiveness of Oral Minoxidil in Children: A Systematic Review Dermatology and therapy · 2024
    24. The use of platelet‐rich plasma in wound healing and vitiligo: A systematic review and meta‐analysis Skin Research and Technology · 2023
    25. Facial Feminization: Systematic Review of the Literature 2016 · 157 citations
    26. Systematic Review: Allogenic Use of Stromal Vascular Fraction (SVF) and Decellularized Extracellular Matrices (ECM) as Advanced Therapy Medicinal Products (ATMP) in Tissue Regeneration International Journal of Molecular Sciences · 2020 · 113 citations
    27. Safety Profile for Microneedling: A Systematic Review Dermatologic surgery · 2021 · 17 citations
    28. Association between Mesenchymal Stem Cells and COVID-19 Therapy: Systematic Review and Current Trends BioMed Research International · 2022 · 4 citations
    29. Lasers and Energy-Based Devices in The Treatment of Androgenetic Alopecia: A Systematic Review and Meta-analysis Skin Appendage Disorders · 2026
    30. Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence Across Alopecia Types and Exosome Sources Clinical Cosmetic and Investigational Dermatology · 2025