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A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Reconstruct lips with proper planning, templates, and revisions for appearance and function.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Finasteride helps reduce heart issues and improves heart function.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Keratinocytes control how melanocytes work.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

The flexible fixed-sequence testing method allows for more effective evaluation of multiple goals in a clinical trial while controlling the risk of false positives.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.