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    Did you mean Retinoid X Receptor?
    Glossary Retinoid X Receptor

    regulates gene expression by binding to specific DNA sequences

    The Retinoid X Receptor (RXR) is a type of nuclear receptor that plays a crucial role in regulating gene expression. It binds to specific DNA sequences and partners with other receptors to control various biological processes, including cell growth, differentiation, and metabolism. RXRs are important in the context of skin health and hair growth, as they can influence the activity of genes involved in these processes.

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    1. Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes 2000 · 15 citations
    2. Expression of retinoid-X receptors (-Æ,-a,-a) and retinoic acid receptors (-Æ,-a,-a) in normal human skin: an immunohistological evaluation 1997
    3. Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth. Acta Dermato Venereologica · 1997 · 34 citations
    4. Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development. Blood · 2004 · 2 citations
    5. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations
    6. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    7. The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events. PubMed · 1998 · 44 citations
    8. Research on Expression of Retinoid-related Orphan Receptor (ROR) in the Skin of Cashmere Goat China Animal Husbandry & Veterinary Medicine · 2010
    9. Association Between Retinoid X Receptor Gene Variants and Dyslipidemia Risk in an Iranian Population Cureus · 2021 · 1 citations
    10. Novel Drugs Targeting Retinoic Acid Receptors 2005
    11. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    12. Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis 2015
    13. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    14. Retinoids Putting the “A” in Alopecia Journal of Investigative Dermatology · 2013 · 7 citations
    15. Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis - eScholarship 2015
    16. 1410 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration 2018
    17. The Molecular Biology of the Vitamin D Receptor Humana Press eBooks · 2010 · 22 citations
    18. Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands Journal of bone and mineral research · 2007 · 137 citations
    19. Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets due to a Mutation Causing Multiple Defects in Vitamin D Receptor Function Endocrinology · 2004 · 67 citations
    20. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    21. Analysis of 1,25-Dihydroxyvitamin D3 Receptors (VDR. in Basal Cell Carcinomas ˜The œAmerican journal of pathology · 1999 · 42 citations
    22. Retinoids Clinical approaches and procedures in cosmetic dermatology · 2017
    23. MULTISYSTEM ADVERSE EFFECTS OF ISOTRETINOIN: MECHANISTIC INSIGHTS AND CLINICAL IMPLICATIONS International Journal of Innovative Technologies in Social Science · 2026
    24. α-Mangostin, a safe and natural product as a candidate skin-whitening agent Scientific Reports · 2025
    25. Effect of calcium supplementation on bone deformity and histopathological findings of skin papules in a pediatric patient with vitamin D–dependent rickets type 2A: a case report Clinical Pediatric Endocrinology · 2025
    26. From molecular biology to therapeutics 1994 · 7 citations
    27. GLP-1 RAs and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions 2025
    28. Hormones and the pilosebaceous unit Dermato-endocrinology · 2009 · 97 citations
    29. Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids FASEB bioAdvances · 2021 · 13 citations
    30. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne 2009 · 65 citations