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    Did you mean Retinoid X Receptor?
    Glossary Retinoid X Receptor

    regulates gene expression by binding to specific DNA sequences

    The Retinoid X Receptor (RXR) is a type of nuclear receptor that plays a crucial role in regulating gene expression. It binds to specific DNA sequences and partners with other receptors to control various biological processes, including cell growth, differentiation, and metabolism. RXRs are important in the context of skin health and hair growth, as they can influence the activity of genes involved in these processes.

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    Research 30 of 1000+

    1. Expression of retinoid-X receptors (-Æ,-a,-a) and retinoic acid receptors (-Æ,-a,-a) in normal human skin: an immunohistological evaluation 1997
    2. Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes 2000 · 15 citations
    3. Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development. Blood · 2004 · 2 citations
    4. Novel Drugs Targeting Retinoic Acid Receptors 2005
    5. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations
    6. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    7. Cellular localization of retinoic acid receptor-gamma expression in normal and neoplastic skin. PubMed · 1992 · 23 citations
    8. Prediction and Demonstration of Retinoic Acid Receptor Agonist Ch55 as an Antifibrotic Agent in the Dermis Journal of Investigative Dermatology · 2023 · 3 citations
    9. Expression of retinoic acid receptors and dermal-epidermal interactions during mouse skin morphogenesis 1992 · 3 citations
    10. Hair Vibrissa Follicle Morphogenesis is Linked to the Expression of Retinoic Acid Receptors α and γ Genes Biology of the Cell · 1992
    11. Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle 2007 · 48 citations
    12. Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells Biomolecules · 2025
    13. Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3 Animals · 2024
    14. The Retinoic-Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting International Journal of Molecular Sciences · 2025
    15. Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia Journal of Investigative Dermatology · 1998 · 10 citations
    16. Association Between Retinoid X Receptor Gene Variants and Dyslipidemia Risk in an Iranian Population Cureus · 2021 · 1 citations
    17. Retinoic Acid and Mouse Skin Morphogenesis. I. Expression Pattern of Retinoic Acid Receptor Genes During Hair Vibrissa Follicle, Plantar, and Nasal Gland Development Journal of Investigative Dermatology · 1994 · 24 citations
    18. Dermal Papilla Cells from Human Hair Follicles Express mRNA for Retinoic Acid Receptors in Culture Annals of the New York Academy of Sciences · 1991 · 9 citations
    19. A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11 Mammalian Genome · 1998 · 76 citations
    20. Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth. Acta Dermato Venereologica · 1997 · 34 citations
    21. Hypothesis: Wound‐induced TLR3 activation stimulates endogenous retinoic acid synthesis and signalling during regeneration Experimental dermatology · 2019 · 5 citations
    22. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    23. Effects of all-trans retinoic acid on goat dermal papilla cells cultured in vitro Electronic Journal of Biotechnology · 2018 · 4 citations
    24. All-trans retinoic acid modulates proliferation and apoptosis of secondary hair follicle–dermal papilla cells in cashmere goats via the TGF-β2/Smad2/3 pathway Frontiers in Veterinary Science · 2026
    25. All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway Acta histochemica · 2020 · 10 citations
    26. 1410 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration 2018
    27. Retinoic Acid and Mouse Skin Morphogenesis. II. Role of Epidermal Competence in Hair Glandular Metaplasia Developmental Biology · 1994 · 16 citations
    28. Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid PloS one · 2017 · 2 citations
    29. Combination of All-Trans Retinoic Acid Resumes the Sustained Response of TPO-RA in ITP Blood · 2024
    30. The Molecular Biology of the Vitamin D Receptor Humana Press eBooks · 2010 · 22 citations