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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

PCOS is caused by both genetics and environmental factors like diet and obesity.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Different types of skin cells play specific roles in development, healing, and cancer.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Sulforaphane from broccoli can help protect skin from sun damage.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Hair loss in men is common, treatable, but not curable.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.