2 citations
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March 2022 in “Modern Rheumatology Case Reports” In this study, a case of a patient with dermatomyositis and alopecia universalis showed successful treatment with tofacitinib, suggesting potential responsiveness to janus kinase inhibitors.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
1 citations
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August 2023 in “Military Medical Research” This review discusses recent advancements in responsive-hydrogel dressings for diabetic wound healing, highlighting their design, responsiveness, and degradation behavior, and evaluating their potential advantages and limitations in clinical applications.
1 citations
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November 2016 in “Frontiers in neurology” In this case report, a patient with Cronkhite-Canada syndrome also had mononeuritis multiplex, and the authors suggest that an autoimmune mechanism may be involved based on steroid responsiveness and electrophysiological findings.
March 2026 in “Immunological Medicine” This review discusses the use of Janus kinase inhibitors for severe alopecia areata in Japan, noting their effectiveness in some patients but highlighting the need for new therapies due to non-responsiveness and relapse in others; it reports no new clinical results.
January 2026 in “British Journal of Dermatology” This study found that neither caffeine nor N,N-dimethylglycine treatments were toxic to balding or nonbalding dermal papilla cells and could stimulate calcium influx, indicating treatment responsiveness.
January 2014 in “theses.fr (ABES)” In this research, Sertoli cell line model ST38c demonstrated that the androgen receptor regulates hormone pathways through specific coregulators, suggesting roles for SRC-2 and HBO1 in testicular development and androgen responsiveness.
8 citations
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July 2020 in “Dermatologic Therapy” Tofacitinib may effectively treat folliculitis decalvans.
17 citations
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January 1984 in “Psychotherapy and psychosomatics” This study reported that 44% of hirsute women undergoing cyproterone acetate treatment experienced impaired sexual enjoyment, highlighting the need to inform patients about potential side effects.
7 citations
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November 2025 in “Journal of Polymer Science” This review highlights recent advances in hydrogel-based wound healing, noting that diverse hydrogel designs enhance healing and suggest potential for clinical translation, albeit with a need for more research on human applications.
118 citations
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August 2010 in “Developmental Cell” This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.
61 citations
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October 2013 in “PLoS ONE” This study found that amplifying Wnt signaling, either genetically or through topical application of liposomal Wnt3a, improved skin wound healing in a mouse model.
29 citations
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December 1998 in “European Respiratory Journal” This study found that exposure to hair bleach aerosols containing persulphates and hydrogen peroxide induced airway hyperresponsiveness to acetylcholine in rabbits.
12 citations
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April 2016 in “PLoS ONE” This study found that the Chinese version of the Polycystic Ovary Syndrome Quality of Life Questionnaire (Chi-PCOSQ) is sensitive to clinical changes and effectively assesses health-related quality of life in Chinese women with PCOS.
6 citations
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September 2023 in “Experimental physiology” In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.
This study found that the transcription factor Lhx2 regulates Sonic Hedgehog signaling in mouse retinal progenitor cells, mainly by controlling the expression of co-receptors essential for effective pathway activation during early retinal neurogenesis.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” This study found that TRPA1-deficient mice exhibited normal cold sensitivity but had decreased mechanical response in nociceptors, suggesting TRPA1's role in mechanotransduction.
227 citations
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April 2020 in “Cell” This review highlights the ongoing challenges and advancements in developing precise and early intervention strategies for autoimmune diseases and emphasizes the need for more personalized and disease-specific therapies.
126 citations
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October 2012 in “PLoS ONE” This study found that reduced cytokinin levels allow plants to adapt to low potassium conditions by enhancing root hair growth, reactive oxygen species accumulation, and expression of a key potassium transporter gene.
80 citations
,
December 1996 in “Pain” This study found that spinal strychnine enhances low threshold tactile responses in cat dorsal horn neurons, which may mirror pain states in humans that are less responsive to opioid treatments.
68 citations
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March 2019 in “Advanced Healthcare Materials” This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.
57 citations
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October 1996 in “Dermatologic clinics” This study found that using hyaluronic acid microneedles to deliver minoxidil significantly reduced hair loss in chemotherapy-induced alopecia mice, with only 10% of the dose used in topical applications.
52 citations
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January 2016 in “Brazilian Journal of Medical and Biological Research” In this study, patients with generalized vitiligo treated with a combination of oral compound glycyrrhizin and UVB light showed the most effective repigmentation and disease stabilization compared to other treatment groups.
52 citations
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March 2007 in “Dermatologic Therapy” This article describes the development and validation of a standardized instrument for measuring skin involvement in cutaneous lupus erythematosus, aiming to aid future clinical research and trials.
38 citations
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August 2005 in “Veterinary dermatology” This study demonstrates that exfoliative cutaneous lupus erythematosus in German short-haired pointers involves a cellular and humoral immune response against the epidermal basement membrane, with poor response to immunosuppressive therapy.
37 citations
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September 2018 in “The Journal of Clinical Endocrinology and Metabolism” This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.
26 citations
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August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.
24 citations
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March 2010 in “Value in Health” This review found that the only PCOS-specific quality of life measure, the PolyCystic Ovary Syndrome Questionnaire, has an incomplete development history and lacks some essential measurement properties for clinical trial use.
21 citations
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December 2014 in “Clinics in dermatology” This review discusses squaric acid dibutylester's use, effects, and safety in treating alopecia areata, but reports no new clinical results.
19 citations
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January 1991 in “PubMed” This case study reported that glucocorticoid treatment markedly improved all clinical features in a girl with generalized komuragaeri disease, suggesting potential autoimmune involvement in the disease's pathogenesis.