November 2024 in “Skin Appendage Disorders” In this study, researchers assessed the quality of life in patients with different types of alopecia using the Skindex-29 and DLQI questionnaires, finding that telogen effluvium and alopecia areata had the greatest pretreatment impact on quality of life, with moderate responsiveness observed after treatment.
3 citations
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January 2022 in “Journal of neuroendocrinology” This study found that Arc/Arg3.1 expression in hippocampal neurons is regulated by sex steroids in a sex-dependent manner, with E2 increasing expression in females and DHT in males.
This study concluded that removing alopecia and mucous membrane components from the CLASI-A score limits the ability to capture crucial clinical information about cutaneous lupus erythematosus activity, recommending their retention.
March 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that alopecia areata patients often had low vitamin D levels, and topical calcipotriol treatment significantly reduced the severity of their hair loss.
October 2023 in “Journal of Pakistan Association of Dermatologists” This randomized control trial reported that patients with alopecia areata typically have lower serum Vitamin D levels, and treatment with topical vitamin D3 analogue calcipotriol led to significant hair regrowth in 71% of participants over six months.
1 citations
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July 2020 in “The Egyptian Journal of Hospital Medicine” This study found no significant association between the MDR1 C3435T polymorphism and methotrexate responsiveness in rheumatoid arthritis patients.
In these randomized, placebo-controlled trials, patients with alopecia areata who received baricitinib showed significantly higher eyebrow and eyelash hair regrowth rates compared to placebo, with greater responses observed at the 4 mg dose and in those achieving overall scalp hair improvement by Week 52.
21 citations
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November 2017 in “Scientific Reports” This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.
1 citations
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July 2025 in “Biomaterials Advances” This study investigated how 2D and 3D cell culturing methods influence hair follicle morphogenesis, finding that 3D cultures responded more expectedly to minoxidil while 2D cultures reacted better to DHT treatment, challenging the assumption that 3D cultures are always superior.
January 2024 in “Journal of advanced research in Medical and Health science” This study observed that vitamin D deficiency in alopecia areata correlates inversely with disease severity and duration, but does not correlate with serum vitamin D levels.
September 2023 in “International Journal of Trichology” In this case series, the authors reported effective hair regrowth and resolution of symptoms in three pediatric patients with folliculitis decalvans following treatment with a combination of antibiotics, retinoids, dapsone, and corticosteroids.
April 2009 in “Journal of Pain” Finasteride reduces pain in male rats and works better with testosterone.
13 citations
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April 2021 in “Value in Health” This review categorizes 59 modifications of the Dermatology Life Quality Index across multiple studies, highlighting the need for further validation of these customized health-related quality of life tools in dermatology.
63 citations
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December 2013 in “PLoS ONE” This study suggests that finasteride may reduce the aggressiveness and invasion of prostate tumors, with effects potentially differing based on the androgen responsiveness of the patient's prostate cells.
56 citations
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October 2018 in “Journal of The American Academy of Dermatology” This review discusses the role of androgens in women's skin-related conditions like acne, hirsutism, and female pattern hair loss, noting the lack of dermatology guidelines for when to pursue endocrinologic evaluation.
31 citations
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November 2016 in “Cell Reports” This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.
22 citations
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October 2012 in “Cell Transplantation” This study found that adding Wnt-10b to the culture medium of dermal papilla cells maintained their ability to induce hair follicles over 100 days in vitro.
13 citations
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October 2010 in “Methods in molecular biology” This article discusses the development and research applications of human hair follicle organ culture techniques, highlighting its potential to explore biological processes beyond dermatology.
August 2025 in “Journal of Cosmetic Dermatology” This review explores low-level light therapy's potential as a noninvasive treatment for various forms of alopecia, noting its promising results in hair regrowth and density but highlighting the need for standardized protocols and further research.
April 2018 in “Journal of Investigative Dermatology” This study observed that, contrary to common belief, aged Balb/C mice showed better wound healing than younger mice despite greater weight loss, possibly due to increased T regulatory cells.
1 citations
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January 1971 Hormones, especially androgens, affect hair growth and can cause hair loss or excess hair in both men and women.
50 citations
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October 1986 in “European journal of pediatrics” This case study reported that absence of alopecia does not reliably predict responsiveness to vitamin D treatment in Vitamin D-dependent rickets type II, as demonstrated by a patient with normal hair growth who showed extreme resistance.
12 citations
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June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
3 citations
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May 2025 in “Journal of Applied Polymer Science” This study developed a multifunctional, sprayable hydrogel with temperature responsiveness, showing strong antimicrobial properties against E. coli and S. aureus, antioxidant activity, and cytocompatibility, indicating potential for wound healing applications.
2 citations
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September 1971 in “Metabolism, clinical and experimental” In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.
144 citations
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September 2006 in “Clinics in Dermatology” This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
21 citations
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June 2024 in “Pharmaceuticals” This review examines the potential of swellable microneedles in drug delivery and diagnostics, highlighting innovations and challenges in their use for chronic disease treatment, but noting that issues like physiological responsiveness and long-term stability still require research.
16 citations
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March 2015 in “Dermatologic therapy” This study reported two cases of alopecia areata where hair regrowth was achieved with zinc gluconate and sulfur amino acids after relapse post-PUVA cessation, suggesting potential zinc responsiveness in some patients.
9 citations
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June 2019 in “JAAD case reports” This report discusses laser hair removal for acne keloidalis nuchae, noting generally favorable outcomes but variability in lesion responsiveness and a need for standardized assessment criteria; it reports no new results.
8 citations
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November 2024 in “Acta Dermato Venereologica” This review summarizes existing validation research on the Dermatology Life Quality Index (DLQI), highlighting its reliability and responsiveness while identifying the need for further validation regarding racial and ethnic inclusivity.