research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research Hyperandrogenism in Women: Polycystic Ovary Syndrome
The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
research A Systematic Review of Models of Care for Polycystic Ovary Syndrome Highlights the Gap in the Literature, Especially in Developing Countries
The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.
research Creating a Survey Instrument for Self-Assessed Menstrual Cycle Characteristics and Androgen Excess
In 2020, a new online survey was made to help identify Polycystic ovary syndrome (PCOS) in women, but it needs some improvements for better understanding and accuracy.
research Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals
Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
research Female Pattern Hair Loss and Polycystic Ovarian Syndrome: More Than Just Hirsutism
Female pattern hair loss is common in women with polycystic ovarian syndrome.
research Geographical Differences in Demographics and Fertility Histories of Men Presenting for Infertility Evaluation Between the United States and Canada: Results from the Andrology Research Consortium
American men seeking infertility evaluation are generally older, more obese, have longer infertility duration, and different lifestyle habits compared to Canadian men.
research Safety and Tolerability of Antiepileptic Drugs in Women with Epilepsy
Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.
research An Expert System for Clinical Risk Assessment of Polycystic Ovary Syndrome Under Uncertainty
The document concludes that the new expert system can assess the risk of PCOS effectively despite uncertainties in diagnosis.
research Analysis of the Quality, Accuracy, and Readability of Patient Information on Polycystic Ovarian Syndrome (PCOS) on the Internet: A Cross-Sectional Study
The internet has accurate information on Polycystic Ovarian Syndrome, but it's not high quality or easy to read, so we need better, user-friendly resources.
research The Role of Leucaena in Cattle Fattening and Breeding Production Systems in Eastern Indonesia
Leucaena feed helps farmers grow larger cattle herds and is good for fattening, but its safety for breeding cows is unclear.
research The Role of Polycystic Ovarian Syndrome in Chronic Inflammation, Psychological Health, and the Gut Microbiota State: A Case Report
Polycystic Ovarian Syndrome (PCOS) can cause chronic inflammation, mental health issues, and changes in gut bacteria, but a holistic lifestyle change can significantly improve these conditions.
research Knowledge About Polycystic Ovarian Syndrome and Effect of Lifestyle Habits Among Medical Students of North India
Most medical students in North India know about PCOS and how lifestyle changes can affect it; early screening is important to prevent complications.
research Influence of Lifestyle on the Prognosis of Polycystic Ovary Syndrome
Healthy lifestyle changes, especially weight loss, can improve symptoms and overall health in people with Polycystic Ovary Syndrome, especially if they are overweight or obese.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Living with Grief: A Phenomenological Analysis of the Lived Experience of PCOS
Women with PCOS need more support to cope with isolation, helplessness, and grief, and to build resilience.
research Diphenyl Cresyl Phosphate [MAK Value Documentations, 2003]
Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.
research The Curative Effect of Metformin in Combination with Dyne-35 on the Treatment of Polycystic Ovary Syndrome and on the Ovulation Rate and Pregnancy Rate
Metformin combined with dyne-35 increases ovulation and pregnancy rates in PCOS patients.
research Epidemiology, Diagnosis, and Management of Polycystic Ovary Syndrome
PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.
research Polycystic Ovary Syndrome and Infertility: An Update
New treatments for PCOS are improving fertility and managing symptoms better.
research Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period
Finasteride causes lasting fertility decrease in rats.
research Polycystic Ovary Syndrome and Sexual Dysfunctions
Women with PCOS often have sexual problems, and treating these issues early can improve satisfaction and reduce healthcare costs.
research Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility
Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
research Global Impact of Coronavirus Disease 2019 (COVID-19)
COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.
research Obtaining a Pregnancy in Women with Polycystic Ovary Syndrome Using Myo-Inositol
Myo-inositol-based treatments greatly improve pregnancy chances for women with PCOS.
research Potential Pharmacological Activities of Pumpkin Seeds as a Functional Food: A Comprehensive Review
Pumpkin seeds may improve health due to their rich nutrients and potential to treat various conditions.
research Detection of Cortisol, Estradiol, and Testosterone in Archaeological Human Hair from the Dakhleh Oasis, Egypt
Ancient hair can preserve hormones, revealing health and fertility insights.
research Does Imipramine and Pseudoephedrine Medical Treatment Have Clinical Implications in the Treatment of Retrograde Ejaculation Caused by Diabetes Mellitus?
Imipramine and pseudoephedrine treatment can effectively restore normal ejaculation in patients with diabetes, increasing their chances for pregnancy.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Geographical Differences in Male Infertility Between the United States and Canada: Insights From the Andrology Research Consortium
American men are older, more obese, and have longer infertility than Canadian men.