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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Polish medical societies recommend personalized treatment for PCOS based on the patient's specific symptoms and use the Rotterdam criteria for diagnosis.

Hair style affects perceptions of age, health, and attractiveness more than hair color does.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.

About 7% of Omani women visiting a gynecology clinic had polycystic ovarian syndrome, similar to rates in other countries.

Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.

Thyroid hormone treatments help thyroidectomized rats grow normally.

The free androgen index varies among women with different types of PCOS.

PCOS significantly affects women's mental health, and more research is needed to develop effective treatments for these issues.