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    Research 181–210 of 1000+

    1. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
    2. Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats Pharmacology Biochemistry and Behavior · 2010 · 13 citations
    3. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    4. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    5. Plasma androsterone/epiandrosterone sulfates as markers of 5α-reductase activity: Effect of finasteride in normal men Steroids · 1997 · 13 citations
    6. The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia Physiology & Behavior · 2018 · 12 citations
    7. Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor <em>in Vitro</em> Pharmacology & pharmacy · 2018 · 12 citations
    8. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    9. Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity Endocrine journal · 1998 · 12 citations
    10. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    11. Metabolic dysfunction in female mice with disruption of 5α-reductase 1 2017 · 11 citations
    12. Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days The Journal of Urology · 2010 · 11 citations
    13. Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals European Journal of Drug Metabolism and Pharmacokinetics · 2008 · 11 citations
    14. 5α-Reductase and 11β-Hydroxysteroid Dehydrogenase Activity in Prepubertal Hispanic Girls with Premature Adrenarche The Journal of Clinical Endocrinology & Metabolism · 2002 · 11 citations
    15. Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia Archives of Dermatology · 1997 · 11 citations
    16. Is there a role for 5α‐reductase inhibitors in transgender individuals? International Journal of Andrology · 2020 · 10 citations
    17. Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study International Journal of Environmental Research and Public Health · 2019 · 10 citations
    18. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    19. Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride International Journal of Andrology · 2010 · 10 citations
    20. Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride Analytica Chimica Acta · 2010 · 10 citations
    21. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    22. Greater conversion of testosterone to 5α-dihydrotestosterone, reflecting increased peripheral 5α-reductase activity in nude mice treated with high doses of cyclosporine A Journal of Steroid Biochemistry · 1990 · 10 citations
    23. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    24. Die pathogenetische Bedeutung der 5α-Reduktase-Isoenzyme für die androgenetische Alopezie Der Hautarzt · 1999 · 9 citations
    25. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations
    26. Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing BMC Biology · 2022 · 8 citations
    27. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder Journal of Clinical Investigation · 2021 · 8 citations
    28. Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids The Journal of Clinical Endocrinology and Metabolism · 2020 · 8 citations
    29. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    30. Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction Mass spectrometry letters · 2012 · 8 citations