Search
for

    Sort by

    Research 151–180 of 1000+

    1. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations
    2. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    3. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    4. Development of a new gas chromatography–mass spectrometry (GC–MS) methodology for the evaluation of 5α-reductase activity Talanta · 2013 · 17 citations
    5. Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach European journal of medicinal chemistry · 2012 · 17 citations
    6. A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2011 · 17 citations
    7. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    8. 5α-Reductase Inhibitors, Chemical and Clinical Models Steroids · 1998 · 17 citations
    9. 5α‐Reductase Inhibitors Andrology · 1997 · 17 citations
    10. FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 17 citations
    11. The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance Journal of Ethnopharmacology · 2018 · 16 citations
    12. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    13. Enhanced skin permeation of 5α-reductase inhibitors entrapped into surface-modified liquid crystalline nanoparticles Archives of Pharmacal Research · 2014 · 16 citations
    14. 5α-Reductase Inhibitors (5ARIs) and Male Reproduction Advances in Experimental Medicine and Biology · 2017 · 15 citations
    15. Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression Biological & Pharmaceutical Bulletin · 2016 · 15 citations
    16. 5α-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis Hormone Molecular Biology and Clinical Investigation · 2014 · 15 citations
    17. Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population Gene · 2013 · 15 citations
    18. Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size Steroids · 2009 · 15 citations
    19. Finasteride, a 5α-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat Hormones and Behavior · 2007 · 15 citations
    20. 5alpha-reductase inhibitors - a new hope in dermatology? International Journal of Dermatology · 1997 · 15 citations
    21. The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats Translational Stroke Research · 2018 · 14 citations
    22. Equine 5α-reductase activity and expression in epididymis Journal of Endocrinology · 2016 · 14 citations
    23. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors Steroids · 2011 · 14 citations
    24. In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole Drug Metabolism and Disposition · 2011 · 14 citations
    25. A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets Brain Research Protocols · 2002 · 14 citations
    26. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    27. Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice Neuroscience · 2020 · 13 citations
    28. Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency Endocrine journal · 2019 · 13 citations
    29. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors Chemical & Pharmaceutical Bulletin · 2017 · 13 citations
    30. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids Steroids · 2015 · 13 citations