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Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

MK-386 reduces sebum DHT levels.

Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

The β-sitosterol hair gel is effective and promising for treating hair loss.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Ergostadienol from Moringa seed oil may help prevent hair loss.

Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Finasteride may help reduce opioid use.

The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

HST and HST/F promote hair growth and may help treat alopecia.

Dutasteride improved both hair loss and acne in two young men.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Finasteride improves hair growth in men with androgenetic alopecia.

Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride effectively blocks enzyme causing male pattern baldness.

Four-amino acid part makes enzyme sensitive to finasteride.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.