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    Research 91–120 of 1000+

    1. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    2. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells Biochemical and Biophysical Research Communications · 2007 · 34 citations
    3. Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp Journal of Dermatological Science · 1999 · 34 citations
    4. Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015 · 33 citations
    5. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    6. In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles Journal of Pharmaceutical Sciences · 2017 · 32 citations
    7. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    8. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017 · 31 citations
    9. The Effect of 5 -Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008 · 31 citations
    10. 5α-Reductase inhibitors in androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 29 citations
    11. Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase BJU international · 2009 · 29 citations
    12. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    13. Long-term use of 5α-reductase inhibitors and the risk of male breast cancer Cancer Causes & Control · 2014 · 28 citations
    14. Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles Archives of Dermatological Research · 1999 · 28 citations
    15. Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5α-reductase inhibitor Reproductive Toxicology · 1991 · 28 citations
    16. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    17. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation Neuropsychopharmacology · 2017 · 27 citations
    18. The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease Neuropharmacology · 2015 · 27 citations
    19. In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors The Journal of Steroid Biochemistry and Molecular Biology · 2008 · 27 citations
    20. Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase Journal of Medicinal Chemistry · 2001 · 27 citations
    21. 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction Neurobiology of Disease · 2018 · 26 citations
    22. 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives International Journal of Biological Macromolecules · 2011 · 26 citations
    23. 5alpha-reductase 2 inhibition impairs brain defeminization of male rats: Reproductive aspects Pharmacology Biochemistry and Behavior · 2005 · 26 citations
    24. Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment Neurobiology of Aging · 1995 · 26 citations
    25. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations
    26. In vivo evidence for an increase in 5alpha‐reductase activity in the rat central nervous system following morphine exposure International Journal of Developmental Neuroscience · 2005 · 25 citations
    27. Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 25 citations
    28. The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase? Journal of neuroendocrinology · 2013 · 24 citations
    29. Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes <i>In Vitro</i> Hormone and metabolic research · 2007 · 24 citations
    30. 5α-reductase inhibitors/finasteride The Prostate · 1996 · 24 citations