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    Research 61–90 of 1000+

    1. Actions of 5α-reductase inhibitors on the epididymis Molecular and Cellular Endocrinology · 2006 · 48 citations
    2. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. PubMed · 1999 · 48 citations
    3. The extract of Thujae occidentalis semen inhibited 5α-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse Journal of dermatological science · 2003 · 47 citations
    4. Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness Journal of Investigative Dermatology · 2001 · 47 citations
    5. Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5α-reductase II Advances in Therapy · 2010 · 46 citations
    6. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations
    7. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    8. New 5?-reductase inhibitors: In vitro and in vivo effects Steroids · 2005 · 45 citations
    9. Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin Archives of dermatology · 2000 · 45 citations
    10. Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 2005 · 44 citations
    11. Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase Scientific Reports · 2016 · 43 citations
    12. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice Psychoneuroendocrinology · 2012 · 42 citations
    13. Anabolic effects of testosterone are preserved during inhibition of 5α-reductase 2007 · 42 citations
    14. Steroid 5α-Reductase Inhibitors Mini-reviews in Medicinal Chemistry · 2003 · 42 citations
    15. PNU 157706, a novel dual type I and II5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 42 citations
    16. Apparent Cortisone Reductase Deficiency: A Rare Cause of Hyperandrogenemia and Hypercortisolism Hormone Research in Paediatrics · 2000 · 41 citations
    17. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    18. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    19. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    20. Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase. PubMed · 2005 · 38 citations
    21. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    22. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    23. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog <i>Silurana tropicalis</i> Sexual Development · 2009 · 37 citations
    24. MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 1997 · 37 citations
    25. Decreased fertility in male rats administered the 5α-reductase inhibitor, finasteride, is due to deficits in copulatory plug formation Reproductive Toxicology · 1991 · 37 citations
    26. Intracrine and Myotrophic Roles of 5α-Reductase and Androgens Medicine and science in sports and exercise · 2011 · 35 citations
    27. Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1 Biology of Reproduction · 2004 · 35 citations
    28. Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism Fundamental and applied toxicology · 1994 · 35 citations
    29. 7 Regulation of androgen receptor and 5α-reductase in the skin of normal and hirsute women Clinics in endocrinology and metabolism · 1986 · 35 citations
    30. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations