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This study investigated the effects of a recombinant human collagen complex on hair growth, finding it enhanced survival and function of hair follicle stem cells and promoted hair growth in rat models, suggesting its potential for hair loss prevention and hair health maintenance.

In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.

This study developed a biomimetic 3D skin model with vascularization potential to assess the impact of nano-zinc oxide (nano-ZnO), finding that nano-ZnO significantly influenced genes related to apoptosis, inflammation, and oxidative stress in skin cells.

This study found that recombinant human type XVII collagen (rhCOL17A1) promotes hair growth by activating the Wnt/β-catenin and SHH/GLI signaling pathways and increasing type XVII collagen expression, with significant effects observed in both cell and mouse models.

This study found that Annexin A5 significantly reduced fibrosis and inflammation in both preventive and therapeutic contexts in a bleomycin-induced localized scleroderma mouse model, demonstrating its potential anti-fibrotic and anti-inflammatory effects for treating fibrotic diseases.

This review highlights that collagen XVIIα1's role in maintaining dermal-epidermal junction integrity and hair follicle stem cell maintenance is compromised with age due to reduced levels and increased processing, potentially affecting skin and hair aging.

In this study, treatment with fractional CO2 laser combined with recombinant humanized type III collagen led to significantly better improvements in atrophic acne scars compared to laser treatment with saline, attributed to collagen upregulation and MAPK pathway activation in human dermal fibroblasts.

In this study, a silk fibroin hydrogel containing recombinant NT3 was found to promote scar-less wound healing in a mouse skin injury model by enhancing type III collagen expression and inducing hair follicle formation.

This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.

This review discusses recent advancements and ongoing challenges in engineering human skin with appendages using scaffold-free and scaffold-based bioengineering approaches, but it reports no new clinical results.

This study found that ferulic acid effectively stabilized vitamins C and E in a topical solution, doubling skin photoprotection against solar-simulated irradiation, which may help in preventing photoaging and skin cancer.

This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.

This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.

This study found that postnatal treatment with recombinant EDA normalized adult teeth, improved sweating, and restored normal lacrimation in dogs with XLHED, suggesting its potential as a treatment for the condition.

In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.

This review discusses the integration of biodegradable biomaterials with drugs and stem cells for diabetic wound repair, but reports no new clinical results and highlights the need for further translation to clinical practice.

This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.

This review highlights that hormones significantly influence the wound healing process by coordinating cellular and molecular activities, and hormonal therapy is emerging as a promising treatment, with current research focusing on optimizing dosages and minimizing side effects.

This study found that human hair follicle dermal papilla cells and keratinocytes self-assembled differently in 3D spheroid co-cultures, providing insights into cell distribution and organogenesis during skin regeneration.

This study presents recombinant human hair keratins K31 and K81, observing novel nanostructures from their self-assembly and emphasizing disulfide crosslinking's role in this process.

This study found that the newly developed transdermal oil body microgel emulsion (OBEME) improved wound healing in mice by enhancing skin permeability, reducing inflammation, and promoting new blood vessel formation and re-epithelialization.

This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.

This study reported that plant-produced basic fibroblast growth factor effectively promoted cell proliferation and collagen production in vitro, suggesting potential applications in cosmetics for antiaging and hair growth.

This study found that TSC2-null fibroblast cells from TSC skin hamartomas can induce hair follicle formation and hamartomatous changes in keratinocytes, with active mTOR signaling observable in a mouse xenograft model.

This study found that grafting split-thickness human skin onto nude mice produces scars that mimic hypertrophic scar characteristics in humans, offering a useful model for studying scar formation and treatments.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.

This study found that CYP11A1-derived vitamin D3 analogs inhibit fibroblast proliferation and decrease collagen production through VDR expression, showing potential antifibrotic and antiproliferative activity in human dermal fibroblasts.

This study reported that recombinant human hair keratins, K37 and K81, showed higher purity and enhanced fibrin clot formation compared to traditional extracts, reducing bleeding time and blood loss in rat injury models.