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Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Finasteride reduces movement issues in Parkinson's disease rats.

Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

The study suggests that hypothyroidism may cause alopecia areata.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Sunlight exposure improved a patient's skin condition, and there may be a link between a certain disease and skin growths; a leukemia treatment caused changes in hair color and growth.

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

AIRE deficiency causes hair loss similar to alopecia areata in mice.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Targeting colon cancer stem cells might lead to better treatment results.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

CD4+ skin cells may be precursors to basal cell carcinoma.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Essential oils may help hair health but lack strong scientific proof and can cause allergic reactions.