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Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The drug combination was safe and showed promise in treating advanced tumors.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Early treatment is important for better hair regrowth in elderly women with hair loss.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.