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Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

Sorafenib after liver surgery may increase survival for some liver cancer patients.

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Targeting the Smoothened receptor shows promise for treating certain cancers.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Tamoxifen effectively treats gynecomastia without causing impotence.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.

Eribulin-based chemotherapy is more effective and has fewer side effects for advanced triple-negative breast cancer.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

EGFR-TKIs can cause significant skin, nail, and organ side effects.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

3D cell-derived matrices improve tissue regeneration and disease modeling.

The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.

Certain mice without specific receptors or mast cells don't lose hair from stress.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

The new skin patch with human matrix and antibiotic improves wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.