research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial
Spironolactone most effective for hirsutism, but has side effects.
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research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Intravital Imaging of Hair Follicle Regeneration in the Mouse
Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
research Botulinum Toxin Off-Label Use in Dermatology: A Review
Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling
Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
research Evaluation of the Effects of COVID-19 Pandemic on Hair Diseases Through a Web-Based Questionnaire
The COVID-19 pandemic led to an increase in untreated hair diseases and showed the importance of teledermatology.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Rhythmic Expression of Circadian Clock Genes in Human Leukocytes and Beard Hair Follicle Cells
Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.
research Ruxolitinib for the Treatment of Severe Alopecia Areata
Ruxolitinib can help regrow hair in severe alopecia areata.
research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
research Dermatologic Manifestations of COVID-19: A Comprehensive Systematic Review
COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.
research Crosstalk Between Androgen and Wnt/β-Catenin Leads to Changes in Wool Density in FGF5-Knockout Sheep
Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
research Characteristics of Robotically Harvested Hair Follicles in Koreans
The robotic hair restoration device had a high success rate and was faster than manual methods for Korean patients.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Change of the Diagnostic Distribution in Applicants to Dermatology After COVID-19 Pandemic: What It Whispers to Us?
The COVID-19 pandemic led to fewer dermatology visits and changed the types of skin conditions patients experienced.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Decreased Lipin 1β Expression in Visceral Adipose Tissue Is Associated with Insulin Resistance in Polycystic Ovary Syndrome
Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.
research Liposuction and Tumescent Surgery
Tumescent liposuction is safe and effective for different cosmetic surgeries if done within recommended limits.
research Sleep Problems Are Associated with Development and Progression of Lower Urinary Tract Symptoms: Results from REDUCE
Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Defining the Localization and Molecular Characteristics of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
research Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice
Mice with autoimmune hair loss showed signs of heart problems.
research Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth
Hair follicle regeneration may slow tumor growth.