117 citations
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February 2017 in “American Journal of Clinical Dermatology” This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
60 citations
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December 2015 in “Lasers in Medical Science” This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.
41 citations
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September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
37 citations
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August 2022 in “Frontiers in pharmacology” This study found that oral JAK inhibitors are effective and generally well-tolerated for treating alopecia areata, but high recurrence rates after stopping treatment suggest the need for continuous use.
34 citations
,
October 2018 in “Journal of The American Academy of Dermatology” This review discusses hormone-modulating therapies for androgen-mediated cutaneous disorders in women but reports no new clinical results and highlights the need for more rigorous studies.
32 citations
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September 2016 in “Dermatologic Surgery” This review discusses the current evidence and highlights gaps in research needed for the wider acceptance of low-level laser therapy as a treatment for hair loss; no new clinical results are provided.
25 citations
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March 2017 in “Journal of Dermatological Treatment” This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.
12 citations
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November 2023 in “Medicine” This study used bibliometric analysis to evaluate global research on AI applications in dermatology, identifying 406 relevant papers and highlighting current priorities such as machine learning for wound progression, AI in teledermatology, and applications for skin diseases.
8 citations
,
September 2021 in “Facial plastic surgery & aesthetic medicine” This systematic review found that low-level light/laser therapy showed a positive effect in treating male and female pattern hair loss without side effects, as reported by all analyzed randomized controlled trials.
7 citations
,
February 2022 in “Frontiers in Medicine” This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.
5 citations
,
September 2021 in “Cureus” This paper explores the mechanisms causing depression in women with PCOS and suggests that lifestyle modifications, such as dietary changes and weight loss, as well as cognitive behavioral therapy and antidepressants, can help manage PCOS-induced depression.
3 citations
,
January 2019 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Korean medicine treatments for alopecia often show partial improvement but need more research for standardized guidelines.
1 citations
,
October 2023 in “Dermatology and therapy” This review concluded that baricitinib and other oral JAK inhibitors have the most robust evidence supporting their use in treating severe alopecia areata in adults, compared to other less-evaluated treatments.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
1 citations
,
September 2020 in “Cochrane library (CD-ROM)” This Cochrane Review protocol aims to evaluate the effectiveness and safety of various treatments for alopecia areata through a network meta-analysis, but no specific study findings are reported yet.
This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.
November 2025 in “Journal of Family Medicine and Primary Care” This systematic review and meta-analysis found that low-dose minoxidil treatment effectively enhances facial hair development with relatively minimal side effects, which can be beneficial in primary care settings.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
February 2025 in “PubMed” This article discusses the need for rigorous trials to compare the effectiveness and safety of CAM supplements with conventional dermatologic therapies, reporting no new findings.
September 2023 in “International Journal of Trichology” In this study reviewing recent literature, researchers found limited high-quality evidence supporting the use of adipose-derived stem cells for androgenic alopecia and alopecia areata, suggesting a need for further randomized controlled trials to better assess their efficacy.
This study reviewed evidence suggesting that fire needle therapy may be a potential treatment for alopecia areata; however, it concluded that more evidence-based trials are needed to confirm its efficacy and safety.
January 2019 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study suggests that low level laser therapy may be effective for alopecia compared to placebo, but current evidence is limited and studies show a high risk of bias.
December 2022 in “Journal of dermatology and skin science” This study found that non-Caucasian patients are underrepresented in US RCTs for androgenetic alopecia, limiting the generalizability of the findings to the diverse general population.
August 2022 in “Journal of Cosmetic Dermatology” This study found that 1% topical cetirizine may be more effective than a placebo in treating androgenetic alopecia but appears less effective than minoxidil for hair density, though potentially longer-lasting; however, more well-designed RCTs are needed to confirm these findings.
May 2018 in “Hair transplant forum international” Topical finasteride promotes hair growth with minimal side effects but needs more research for women and optimal use.
8 citations
,
January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
December 2025 in “International Journal of Molecular Sciences” This review examined 40 studies on exosome-based therapies for alopecia areata, reporting significant hair regrowth and improvements in hair count, length, and thickness, but highlighted the need for standardized methodologies and robust RCTs before clinical application.
75 citations
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November 2007 in “Clinical endocrinology” This study found that several drugs, including flutamide and spironolactone, significantly reduced hirsutism in women, with reduced effectiveness in those with higher BMI.
December 2022 in “Skin appendage disorders” This study found that combined therapy of low-level light therapy and minoxidil may offer either superior or equivalent hair regrowth compared to minoxidil alone in treating androgenetic alopecia.
July 2022 in “Journal of Investigative Dermatology” This study analyzed randomized trials on low-level light therapy combined with minoxidil for androgenetic alopecia, reporting either superior or equivalent hair regrowth compared to minoxidil alone, with initial improvements tapering over time.