44 citations
,
October 2011 in “Gynecological Endocrinology” This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.
25 citations
,
February 2012 in “The Journal of Sexual Medicine” In this study, oral finasteride treatment for four weeks reduced the weight of the corpus cavernosum in rats but did not significantly affect erectile function.
25 citations
,
May 2020 in “Stem Cells Translational Medicine” In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.
17 citations
,
December 2018 in “The World Journal of Men s Health” This study concluded that administering dutasteride for more than 8 weeks in rats could lead to irreversible erectile dysfunction, even after stopping the medication.
6 citations
,
February 2012 in “American Journal of Animal and Veterinary Sciences” This review summarizes major growth factors that promote hair follicle growth, but it reports no new experimental findings.
1 citations
,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” In this study, topical acyclovir significantly delayed hair growth initiation and completion in mice and reduced hair follicle size, suggesting potential inhibitory effects on hair growth.
79 citations
,
October 2015 in “Journal of Dermatological Treatment” This review assesses the use of platelet-rich plasma in dermatology and concludes that while there may be modest benefits for certain conditions, more evidence is needed before it can be widely recommended.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
25 citations
,
March 2017 in “Journal of Dermatological Treatment” This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.
2 citations
,
December 2015 in “International Journal of Dermatology” This study found that the washing method can help differentiate chronic telogen effluvium from mild female pattern hair loss, potentially reducing the need for biopsies.
1 citations
,
February 2025 in “Frontiers in Endocrinology” In this study, researchers observed that dietary vitamin D intake and light exposure play a crucial role in vitamin D metabolism in mice, suggesting similar importance for human health in maintaining optimal vitamin D levels.
This chapter reviews the combined use of platelet-rich plasma and microneedling for cosmetic enhancement but reports no clinical results; the authors highlight existing uses and suggest potential synergistic benefits in dermatology.
1 citations
,
November 2019 in “The Korea Journal of Herbology” In this study, a herbal mixture (RAA) was found to promote hair growth in mice, showing increases in hair density and follicle size similar to minoxidil treatment.
February 2025 in “Journal of Nutrients” This research reviews the scientific literature on bone broth extract, exploring its nutritional composition, potential health benefits, food industry applications, and risks such as heavy metal and antibiotic contamination. Results are not reported in this summary.
This monograph reviews the historical and contemporary use of pomegranate in medicine, detailing its chemical components and applications across various medical fields including oncology, dentistry, and urology.
December 2023 in “International Journal of Medical Arts” In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
124 citations
,
January 2012 in “Journal of Allergy and Clinical Immunology” This study found that activation of cannabinoid 1 receptors in human scalp hair follicles may limit excessive mast cell activation and maturation, suggesting a potential therapeutic strategy for managing MC-dependent skin diseases.
32 citations
,
January 2010 in “Journal of Dermatological Science” In this study, Waved-5 mice with reduced EGFR signaling showed nearly normal skin and hair follicle function but experienced a transient reduction in subcutaneous fat.
1 citations
,
July 2024 in “Journal of Investigative Dermatology” MPZL3 protein affects hair growth cycles and could help manage hair loss.
July 2026 in “Journal of Investigative Dermatology” ABS-201 may effectively promote hair growth in men by targeting the prolactin receptor.
November 2025 in “Journal of Investigative Dermatology” NUL-5 may boost hair growth by improving hair follicle health and structure.
July 2025 in “Journal of Investigative Dermatology” BrdU speeds up hair follicle aging and reduces hair quality.
November 2024 in “Journal of Investigative Dermatology” Minoxidil rejuvenates hair follicles and reduces aging signs in male pattern baldness.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
September 2024 in “Journal of the American Academy of Dermatology” This study found that estetrol (E4) significantly prolonged the anagen phase and increased hair matrix keratinocyte proliferation in cultured human hair follicles, suggesting its potential as a treatment for female pattern hair loss.
July 2024 in “Journal of Investigative Dermatology” Topical thyroid hormones may boost hair growth.
July 2024 in “Journal of Investigative Dermatology” Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.
April 2023 in “Journal of Investigative Dermatology” In ex vivo organ culture of human scalp hair follicles, this study found that IL-9 signaling inhibits hair growth, reduces progenitor cell generation, and disrupts immune privilege.