March 2005 in “Journal of The American Academy of Dermatology” This study investigates the potential of a cosmetic day lotion with a 5a-reductase inhibitor and a night lotion with an angiogenic ingredient to modulate hair growth, but reports no clinical results.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.
47 citations
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March 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study identified 43 compounds in Platycladi Cacumen, including flavonoids, and found significant chemical variation in flavonoid content across different regions and processed products.
19 citations
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December 2016 in “PLOS ONE” This study found that proteins secreted by early-passage dermal papilla cells, including SDF1, MMP3, biglycan, and LTBP1, may play significant roles in hair follicle regeneration.
17 citations
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October 1981 in “American Journal of Clinical Nutrition” This study found that individuals with protein-calorie malnutrition, especially those with kwashiorkor, required significantly less force to pluck hair compared to well-nourished patients.
1 citations
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March 2021 in “Frontiers in Medicine” In this study, female pattern hair loss in Chinese Han patients was characterized by decreased hair density and shaft diameter, with minor gender differences and the vertex most affected.
1 citations
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November 2001 in “Acc Current Journal Review” This review found that 5α‐reductase inhibitors were associated with slightly increased rates of decreased libido, erectile and ejaculatory dysfunction, gynecomastia, and mood disorders compared to placebo, though their long-term effects remain unclear.
In this study, the average force required to pluck hair was significantly lower in malnourished adults, especially those with kwashiorkor, compared to well-nourished individuals.
January 2018 in “Surgical and Cosmetic Dermatology” In this study, researchers validated a software-based method that quantitatively assesses the effectiveness of treatments for hair loss by calculating the area of hair loss using contrast in standardized photographs, proving effective for both early and advanced cases of androgenetic alopecia and telogen effluvium.
823 citations
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February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
233 citations
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March 2009 in “Journal of Clinical Oncology” In this study, among patients undergoing chemotherapy for breast or gynecologic cancers, smell and taste functions significantly decreased but largely recovered three months post-treatment, with taxane-based regimens causing more severe taste disturbances.
83 citations
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January 1998 in “Journal of Investigative Dermatology” In this study using human cell cultures, type 1 5α-reductase was found to vary in both protein heterogeneity and expression levels across different types of skin cells.
24 citations
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November 2013 in “British Journal of Dermatology” This study found that chemotherapy in female breast cancer patients caused significant early hair loss, which began to recover three months after completion, whereas tamoxifen did not affect hair growth.
18 citations
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April 1998 in “MIT Press eBooks” This study found that topical application of N,N-dimethylglycine sodium salt increased dermal blood flow and velocity in human subjects, likely through its effects on endothelial cells and NO-dependent vasodilation.
11 citations
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January 1999 in “Dermatologic Surgery” The researchers reported that using extenders during scalp reductions increased effectiveness by 30 to 86% and prevented "stretch-back" in subsequent procedures.
7 citations
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March 2024 in “Scientific Reports” This study reports that the new neighborhood face index (NFI) demonstrates a remarkably high correlation with the physiochemical properties of benzenoid hydrocarbons, highlighting its potential as a predictive tool.
5 citations
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July 2010 in “Journal of life sciences” This study found that gray scalp hair had a higher prevalence of continuous medullation and crenate cuticle type compared to black scalp hair among Bengalee males.
4 citations
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June 2021 in “Frontiers in Pharmacology” This study found that injecting bone marrow-derived mesenchymal stem cells and conditioned medium into mice promoted hair follicle stem cell proliferation and transition to active growth phases, suggesting potential clinical targets for hair loss treatment.
4 citations
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November 2020 in “BMC Dermatology” This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.
4 citations
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April 2001 in “Experimental Dermatology” This study used a novel HPLC-radiomatic flow scintillation system to measure 5α-reductase activity in dermal papillae from miniaturized hair follicles of the human occipital scalp, revealing significant variability in enzyme activity across samples.
2 citations
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February 2025 in “PLoS ONE” This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.
This study found that some white or grey human hairs can naturally regain pigmentation, suggesting a potential temporary reversibility of hair greying associated with stress and molecular changes.
1 citations
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March 2015 in “Journal of Visualized Experiments” This study developed a method to quantify hair loss in mice, aiding the evaluation of new treatments for alopecia.
March 2026 in “Biomedicines” This study found that the Antera 3D® system provided an objective and sensitive method for assessing pediatric pathological scars, capturing significant changes in pigmentation, vascularity, and volume, compared to the traditional Vancouver Scar Scale and dermoscopy, which showed varied sensitivities across different scar parameters.
January 2026 in “International Journal of Cosmetic Science” This study identifies key attributes—luminosity, structural integrity, and vitality—that define hair vibrancy, providing insights to guide the development of hair products that align with consumer expectations.
September 2025 in “Value in Health”
This animal study found that YH0618 may alleviate doxorubicin-induced alopecia and affects proteins like keratin and Smad3, suggesting potential therapeutic targets. The researchers analyzed protein expression changes to understand YH0618's effects in treating chemotherapy-related hair loss.
June 2023 in “Aesthetic Plastic Surgery” This study introduces the PRECISE scale, a quantitative tool to classify androgenetic alopecia, aiming to improve planning and outcomes for hair transplantation surgeries by evaluating the whole hairless and thinning areas.
April 2023 in “Journal of Investigative Dermatology” This study developed a new quantitative method to measure skin cell turnover in just 4 days, showing it can effectively differentiate skincare product performance and revealing that turnover slows with age but responds more to treatments as people get older.
This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.