January 2022 in “Galicia Clínica” This report documents a rare case of alopecia universalis in an HIV-positive patient in Portugal, highlighting the changing comorbidity spectrum in this population due to increased life expectancy from antiretroviral therapy.
In this observational study, researchers found that females and patients with androgenetic alopecia reported significantly greater quality-of-life impairment compared to males and those with alopecia areata.
October 2021 in “Research Square (Research Square)” This study found that in hairpoor mice, disruptions in hair follicle stem cell quiescence and signaling pathways lead to disturbed hair cycles, which may help explain alopecia development in Marie-Unna Hypotrichosis patients.
September 2021 in “Yearbook of pediatric endocrinology” This study found that in mice, chronic stress elevates corticosterone levels, which suppresses hair growth by keeping hair follicles in a prolonged resting phase.
January 2021 in “Scandinavian journal of clinical and laboratory investigation” This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.
This study found that low-intensity light therapy improved quality of life related to emotional, psychosocial, and symptom domains in individuals with androgenic alopecia, with a greater impact observed in women.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the implementation of an integrated medical biochemistry educational program at Bashkent University, designed to enhance students' understanding and application of biochemical processes in clinical settings, and reports no clinical study results.
April 2020 in “Research Square (Research Square)” This study found that oral contraceptives containing cyproterone acetate improved the overall quality of life in PCOS patients more than those containing levonorgestrel after 6 months of treatment.
April 2020 in “International Journal of Cosmetic Science” This study found that improved protein extraction methods enhanced the resolution of hair proteins on gels, but differences in protein abundance between curly and straight Japanese women’s hair were minimal and unlikely to affect hair structure.
This research review concluded that 5α-reductase inhibitors may be effective in treating androgenetic alopecia, showing general efficacy over placebo, though future clinical trials are needed to determine the best drug, dose, and duration, as well as gender differences in treatment response.
February 2020 in “Drug Analytical Research” This study found that magistral topical minoxidil solutions had differences in color, viscosity, and acidity compared to industrial formulations and issues with drug content and dosage indication, despite similar follicular penetration.
December 2019 in “Journal of cosmetic dermatology” This study identified various methodological inconsistencies in systematic reviews on platelet-rich plasma therapy for pattern hair loss, suggesting a need for rigorous adherence to established guidelines.
November 2019 in “Journal of Vertebrate Biology” QIA-64 software can measure straight wire lengths accurately but needs improvement for curved wires and width measurements.
October 2019 in “International journal of contemporary medical research” This study observed that skin diseases had a small to moderate impact on patients' quality of life at a primary healthcare setting, suggesting the need for better training and medication availability for healthcare professionals.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that keloids significantly impair quality of life, with pain and itch being major contributors to this impact, comparable to other chronic dermatologic conditions.
February 2019 in “PubMed” This study explores torsional measurements of single hair fibers to differentiate the effects of cosmetic treatments on hair structure, highlighting their potential to reveal shear stiffness changes related to cuticle damage.
January 2019 in “Analytical Science and Technology” This study developed a rapid method using advanced chromatography and mass spectrometry to detect hair-growth enhancing compounds, discovering synthetic drugs in about 21% of tested supplements.
August 2018 in “Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)” This research observed that chronological age, rather than hearing loss, primarily affects the auditory cortex in aging, and found that brain aging in PolG mice mirrored that of wild-type counterparts, suggesting differential tissue sensitivity to mitochondrial dysfunction.
December 2017 in “Annales de dermatologie et de vénéréologie” This article reviews key developments in pediatric dermatology for 2017, including consensus recommendations, novel genetic findings, and treatment insights for conditions like psoriasis and vascular malformations, without providing new clinical trial results.
September 2017 in “Journal of Investigative Dermatology” QMSI effectively maps and quantifies drug distribution in skin tissues.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.
April 2017 in “Journal of Investigative Dermatology” This study found that a 10% carbamide peroxide solution significantly reduced acne lesions more effectively than a vehicle solution, suggesting it as a safe and effective alternative to benzoyl peroxide for treating mild to moderate acne.
January 2017 in “British journal of dermatology/British journal of dermatology, Supplement” February 2016 in “Science” This research found that Foxc1 promotes quiescence in hair follicle stem cells and identified COL17A1 depletion, due to DNA damage, as a cause of hair thinning and loss during aging.
January 2016 in “Journal of Dr Behcet Uz Children s Hospital” This study examined family functioning, psychopathology, and quality of life in children and adolescents with alopecia areata, analyzing their relationships with sociodemographic and disease-related variables.
May 2014 in “Transfusion and Apheresis Science” The study found that the quality of cord blood units remains consistent before freezing and after thawing, indicating that attached tube segments reliably represent the graft's properties.
August 2013 in “eCommons (Cornell University)” This study found that transcriptional regulation by Runx1 and cyclin-dependent kinase inhibitors plays a crucial role in maintaining quiescence and promoting fate decision flexibility in hair follicle stem cells.
March 2012 in “Korean Journal of Microscopy” This study found that nanoparticles can penetrate the skin, but artifacts produced during specimen preparation complicate accurate observation, and proposed a method for reducing errors in imaging quantum dots as tracers.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
January 2010 in “Actas Dermo-Sifiliográficas” A woman was allergic to quinine in her anti-hair loss lotion.