September 2025 in “BMJ Case Reports” This case report suggests that herpes zoster ophthalmicus with secondary preseptal cellulitis may occur as a rare adverse reaction following platelet-rich plasma injections for androgenetic alopecia.
7 citations
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March 2018 in “Psychiatry and Clinical Psychopharmacology” This article presents five cases of valproate-induced hyperammonemic encephalopathy in psychiatric patients treated at the authors' clinic and discusses existing literature on this side effect.
March 2025 in “Biomedical & Pharmacology Journal” This observational study found that while 96.6% of patients using valproic acid showed the expected clinical response, over half experienced adverse reactions like weight gain, hair loss, and hepatotoxicity, highlighting the need for personalized treatment approaches to minimize these side effects.
42 citations
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January 2003 in “International Journal of Gynecological Pathology” This research observed that multifocal pseudoepitheliomatous hyperplasia may explain some cases of squamous nests in vulvar lichen sclerosus with lichen simplex chronicus, potentially as a reaction to tissue damage rather than squamous cell carcinoma.
July 2026 in “Pediatric Allergy and Immunology”
September 2011 in “Urology” This study aimed to identify characteristics of patients who fail to void during pressure-flow studies, which limits the determination of the cause behind their lower urinary tract symptoms.
This study found that PRP injections may safely improve penile curvature and PDQ scores in men with stable-phase Peyronie's Disease, although the curvature reduction observed was not enough to determine long-term clinical significance.
39 citations
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January 2006 in “Journal of Cosmetic and Laser Therapy” This study found that pneumatic skin flattening (PSF) significantly reduces pain and post-treatment erythema during high-energy IPL and laser hair removal while enhancing treatment efficacy.
2 citations
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April 2024 in “International Wound Journal” Combining UV therapy with PRP heals chronic wounds faster and reduces pain.
6 citations
,
August 1993 in “Archives of Dermatology” This study found that polymorphous light eruption (PLE) may include a wide range of conditions, requiring careful differentiation from similar skin disorders such as benign summer light eruption.
December 2025 in “Scientific Reports” This study found that preconditioning human hair follicle-derived stem cells with valproic acid enhanced their survival and migration in ischemic-like conditions by activating autophagy and inhibiting the AKT/mTOR pathway, suggesting this approach could improve stem cell therapies for ischemic stroke.
5 citations
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February 2018 in “Military medicine” This case study reports a U.S. Naval fighter pilot with recurrent central serous retinopathy who became the first to receive a waiver for unrestricted flight despite permanent defective visual acuity.
March 2015 in “DergiPark (Istanbul University)” This study concluded that topical psoralen and ultraviolet A photochemotherapy is an effective and safe treatment for alopecia areata, as it produced a good response in 43.8% of patients.
January 2023 in “Skin appendage disorders” This case report describes a patient who experienced proton-induced alopecia after proton therapy for a frontal meningioma, which was effectively treated with topical minoxidil, resulting in full hair regrowth after 4 months.
April 2024 in “Lečaŝij vrač” This study found that thrombocytopenia is a common side effect of valproic acid, affecting up to 54% of elderly patients, but it is under-investigated despite significant therapeutic consequences.
December 2020 in “American Journal of Transplantation” This article discusses a journal-based CME activity on rare viral skin eruptions in pediatric transplant patients and reports no new clinical results; it aims to improve physicians' knowledge and treatment of this condition.
January 2026 in “Andrology” This study found that PRP injections are safe and may slightly reduce penile curvature and improve PDQ scores in men with stable-phase Peyronie's Disease, but the changes are not significant enough to predict long-term effects.
6 citations
,
June 2013 in “Toxicological Research” This study found that topical valproate has minimal potential to cause skin irritation, suggesting it can be applied safely to human skin.
19 citations
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October 1996 in “International Journal of Dermatology” This study concluded that pseudopelade is an autosomal dominant condition, distinct from other forms of alopecia, characterized by atrophic hair follicle loss and notable familial association.
April 2012 in “The FASEB Journal” In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.
2 citations
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November 2022 in “IP Indian journal of clinical and experimental dermatology” This study observed that specific dermoscopic features, such as altered pigmentary network and yeast invasion of hair follicles, along with certain histopathological features, assist in diagnosing pityriasis versicolor.
39 citations
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July 2008 in “Dermatologic Therapy” This review provides a practical approach to diagnosing pseudopelade of Brocq and updates on treatment options but reports no new clinical results.
March 2021 in “Indian Journal of Case Reports” This case report describes a young adult female with late-stage Vogt-Koyanagi-Harada disease featuring panuveitis, retinal detachment, hearing loss, alopecia, and vitiligo, who was successfully treated in a hospital.
September 2019 in “Journal of Investigative Dermatology” This study found that a history of smoking significantly predicted a more refractory course of palmoplantar pustulosis, with associated comorbidities often including hypertension, type 2 diabetes mellitus, and thyroid diseases.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This policy brief found that post-drug syndromes are under-recognized in current pharmacovigilance systems, leading to inadequate risk assessments and prolonged patient harm from persistent drug-induced conditions.
This case report describes retinal occlusion and medial canthal swelling in a 64-year-old female following the injection of acellular porcine urinary bladder matrix for hair restoration, a previously unreported side effect.
In this study, Norwegian researchers followed over 350 patients with porphyria cutanea tarda for an average of 7 years and found that 25% experienced biochemical relapse, suggesting the importance of routine follow-up for early detection and management.
1 citations
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January 2025 in “Veterinary Medicine International” This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.
29 citations
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March 1987 in “Therapeutic Drug Monitoring” This study found that venous blood ammonia levels, particularly in patients taking valproate combined with other antiepileptic drugs, were significantly elevated compared to those on valproate alone.
9 citations
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July 2013 in “Clinical Neuroradiology” A man developed a rare blood vessel connection on his scalp after hair transplants, which was successfully treated with surgery.