Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report describes a boy with hypothalamic hamartoma experiencing pubertas precox and gelastic seizures, where leuprorelin therapy's effect on pubertas precox was controversial, but valproic acid effectively managed gelastic seizures.

This study observed that androgen levels rise with pubic hair development in Tanner stages, differing by sex and age, with DHEA showing a significant prepubertal increase especially in precocious adrenarche.

This review discusses factors influencing the earlier onset of puberty, such as obesity and exposure to endocrine-disrupting chemicals, and emphasizes the need for further research and public health policy development.

This case report details the investigation and management of a 3-year-old girl with precocious pseudopuberty due to a Sertoli-Leydig cell tumor, highlighting the importance of early recognition and accurate diagnosis for effective treatment and prognosis.

This case report describes a 19-month-old girl with androgen-dominant virilization caused by an adrenal tumor, highlighting the importance of adrenal assessment in young girls with such symptoms and recommending long-term monitoring even after initial biochemical remission.

This review discusses the challenges in optimizing glucocorticoid treatment for classic 21-hydroxylase deficiency, emphasizing individualized care and the need for comprehensive management, but presents no new findings.

This study identified multiple environmental, dietary, and familial risk factors associated with precocious puberty in girls, such as exposure to cosmetics, frequent consumption of snacks, and mother's early pubertal development.

This case study reports that in an 8-year-old male, a pituitary adenoma causing isolated high LH secretion led to early testosterone-driven puberty without typical testicular enlargement, highlighting the differential roles of LH and FSH in pubertal development.

In this study conducted among healthy Iranian girls in Isfahan province, researchers found that the median onset age for menstruation was 12.05 years, breast development began at 9.89 years, and pubic hair development started at 10.14 years, with earlier puberty onset potentially indicating precocious puberty.

This case study reports that hormonal imbalances in a young boy with precocious pseudopuberty returned to normal after the removal of a testicular interstitial cell tumor, with normal spontaneous puberty following.

This article discusses diagnostic evaluations and management strategies for isosexual precocious puberty, emphasizing the importance of accurate identification and appropriate treatment, but it provides no new clinical findings.

This case report describes a 24-month-old girl from Nigeria with idiopathic precocious puberty, emphasizing the financial barriers to necessary treatment in developing countries.

This case report describes a 7-year-old boy with medulloblastoma who developed central precocious puberty, potentially triggered by the mass effect of the tumor, which was managed with leuprolide.

This study found an association between abnormally high plasma testosterone concentrations and aggressive behaviors in certain autistic individuals.

This study found that women treated with GnRHa for central precocious puberty had a higher prevalence of polycystic ovary syndrome in adulthood compared to those with isolated premature thelarche.

This case report describes a 7.5-year-old girl with precocious puberty displaying significant secondary sexual development and advanced bone age, treated monthly with Leuprolide.

In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

In this study, daughters of women with PCOS and control daughters showed no significant differences in metabolic and hormonal parameters, but more PCOS daughters exhibited hirsutism at advanced pubertal stages.

This report presents a case of familial male-limited precocious puberty with a novel LHCGR gene mutation, where a boy responded well to treatment with bicalutamide and anastrozole.

In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.

This article reviews puberty's onset, development, and the factors affecting it, including nutrition, obesity, and gender dysphoria, and reports no new clinical results.

In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.

This study found that 20% of children initially diagnosed with premature pubarche were later identified with other conditions like central puberty precox or congenital adrenal hyperplasia during follow-up, emphasizing the importance of ongoing differential diagnosis.

This review discusses the potential impact of endocrine-disrupting chemicals and body size on pubertal onset and progression, highlighting critical gaps and priorities for future research without presenting new clinical results.

This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.

This article reviews the characteristics, diagnosis, and management of premature adrenarche and suggests it may predict future ovarian hyperandrogenism in some adolescents; no new clinical results are reported.

This article reviews various aspects of puberty, particularly focusing on the staging of sexual maturity and the factors influencing pubertal onset, but reports no new empirical results.

This review discusses medical interventions that reproductive health experts can provide to transgender and gender diverse youth and reports no new clinical results.

This review discusses the role of oestrogens in stimulating linear bone growth and pubertal changes in both boys and girls, highlighting their influence on the growth hormone-insulin-like growth factor axis; it reports no new clinical results.