Search

for
Search:

GlossaryPhysiotherapy (PT)

uses exercises and manual techniques to treat physical impairments

Physiotherapy, also known as Physical Therapy (PT), is a healthcare profession focused on the assessment, diagnosis, and treatment of physical impairments, disabilities, and pain through various techniques such as exercise, manual therapy, and education. It aims to restore, maintain, and improve a patient's mobility, function, and overall well-being, often following injury, surgery, or the onset of chronic conditions.

Related Terms

Sort by

Research

30 / 1000+ results

Hair Bundle Defects and Loss of Function in the Vestibular End Organs of Mice Lacking the Receptor-Like Inositol Lipid Phosphatase PTPRQ

research Hair Bundle Defects and Loss of Function in the Vestibular End Organs of Mice Lacking the Receptor-Like Inositol Lipid Phosphatase PTPRQ

44 citations, February 2012 in “The journal of neuroscience/The Journal of neuroscience”

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

research Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin

33 citations, May 2006 in “Journal of Investigative Dermatology”

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

research BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy

24 citations, September 2019 in “Experimental cell research”

BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.

research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

23 citations, December 2013 in “Molecular cancer therapeutics”

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells

22 citations, June 2017 in “Stem cell reports”

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Treatment and Prevention of Chemotherapy-Induced Alopecia with PTH-CBD, a Collagen-Targeted Parathyroid Hormone Analog, in a Non-Depilated Mouse Model

research Treatment and Prevention of Chemotherapy-Induced Alopecia with PTH-CBD, a Collagen-Targeted Parathyroid Hormone Analog, in a Non-Depilated Mouse Model

20 citations, September 2013 in “Anti-Cancer Drugs”

PTH-CBD could help prevent and treat hair loss caused by chemotherapy in mice.

research The Relationship Between Eyebrow and Eyelid Position in Patients With Ptosis, Dermatochalasis, and Controls

17 citations, August 2018 in “Ophthalmic Plastic and Reconstructive Surgery”

In ptosis, brow elevation doesn't lift the eyelid but is driven by efforts to raise the eyelid.

research Congenital Ptosis Repair with a Frontalis Silicon Sling: Comparison Between Fox's Single Pentagon Technique and a Modified Crawford Double Triangle Technique

16 citations, July 2017 in “Journal of American Association for Pediatric Ophthalmology and Strabismus”

The modified Crawford technique resulted in less lagophthalmos and better cosmetic outcomes for patients with lateral droop.

research Ptosis in Childhood: Causes, Clinical Presentations, and Management

15 citations, September 2018 in “Medicine”

Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.

research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers

14 citations, October 2018 in “Brain Research Bulletin”

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

research Contrast Enhanced Phototrichogram: An Improved Non-Invasive Technique for Measurement of Scalp Hair Dynamics in Androgenetic Alopecia – Validation Study with Histology After Transverse Sectioning of Scalp Biopsies

12 citations, June 2001 in “PubMed”

CE-PTG is a better method for analyzing hair growth in androgenetic alopecia.

DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

11 citations, March 2014 in “Journal of Investigative Dermatology”

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

research Evidence for Multiple, Developmentally Regulated Isoforms of Ptprq on Hair Cells of the Inner Ear

11 citations, January 2011 in “Developmental neurobiology”

Ptprq has multiple forms that change during inner ear development.

research Lash Ptosis and Associated Factors in Asians

11 citations, August 2010 in “Annals of plastic surgery”

Eyelash drooping is linked to eyelid function and the presence of a double eyelid in Asians, and should be considered in eyelid surgery.

research The Association Between rs2476601 Polymorphism in PTPN22 Gene and Risk of Alopecia Areata

9 citations, May 2019 in “Medicine”

The C-allele and CC-genotype in the PTPN22 gene lower the risk of alopecia areata.

Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

8 citations, March 2014 in “American Journal of Pathology”

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury

6 citations, February 2022 in “The journal of neuroscience/The Journal of neuroscience”

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

research PTP1B Inhibitory and Anti-inflammatory Properties of Constituents from Eclipta Prostrata L.

6 citations, December 2020 in “Biological & Pharmaceutical Bulletin”

Compounds from Eclipta prostrata L. plant have diabetes and obesity-fighting properties and reduce inflammation.

research Ptch2 Is a Potential Regulator of Mesenchymal Stem Cells

3 citations, April 2022 in “Frontiers in Physiology”

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

ERK1/2 Pathway Involvement in Enhancement of Fatty Acids from Phaeodactylum Tricornutum Extract on Hair Follicle Cell Proliferation

research ERK1/2 Pathway Involvement in Enhancement of Fatty Acids from Phaeodactylum Tricornutum Extract on Hair Follicle Cell Proliferation

2 citations, October 2020 in “BioMed Research International”

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

research Prostaglandin D2, Prostaglandin D2 Receptor, Prostaglandin D2 Synthase

2 citations, April 2012 in “Science-business Exchange”

Blocking a protein called prostaglandin D2 might help treat hair loss.

research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata

1 citations, December 2023 in “International journal of molecular sciences”

miR-199a-3p controls hair growth and is linked to alopecia areata.

research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice

1 citations, December 2020 in “International journal of molecular sciences”

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

research Bilateral Nevus Comedonicus of the Eyelids: An Unusual Cause of Ptosis and Ectropion

1 citations, December 2019 in “American journal of ophthalmology. Case reports”

A rare skin condition caused droopy and outward-turning eyelids in a patient.

Nevoid Basal Carcinoma Syndrome (Gorlin Syndrome) and Pronounced Androgenic Alopecia in a Woman with a Novel Mutation p.Leu1159fsx32 in the PTCH Gene

research Nevoid Basal Carcinoma Syndrome (Gorlin Syndrome) and Pronounced Androgenic Alopecia in a Woman with a Novel Mutation p.Leu1159fsx32 in the PTCH Gene

1 citations, September 2011 in “Journal of Dermatology”

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

Comparison of Ruxolitinib and a Collagen-Targeted PTH-Based Hair Cycle Stimulant on Hair Follicle Counts and Hair Growth in the C3H/HeJ Engrafted Mouse Model of Alopecia Areata

research Comparison of Ruxolitinib and a Collagen-Targeted PTH-Based Hair Cycle Stimulant on Hair Follicle Counts and Hair Growth in the C3H/HeJ Engrafted Mouse Model of Alopecia Areata

May 2023

The PTH-CBD injection improved hair regrowth better than the daily ruxolitinib pill in mice.

Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus

research Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus

April 2023 in “Journal of Investigative Dermatology”

PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.

The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata

research The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.

research Comparison of Ruxolitinib and a Collagen-Targeted PTH-Based Hair Cycle Stimulant on Hair Follicle Counts and Hair Growth in the C3H/HeJ Engrafted Mouse Model of Alopecia Areata

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

A PTH-based treatment improved hair regrowth better than ruxolitinib in a mouse model of hair loss.

research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse

March 2023

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.