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    Glossary Psoriasis

    chronic autoimmune condition causing rapid skin cell buildup and scaling

    Psoriasis is a chronic autoimmune condition that causes the rapid buildup of skin cells, leading to scaling on the skin's surface. This buildup forms red patches covered with silvery scales, often accompanied by itching and pain. The most common type is plaque psoriasis, also known as psoriasis vulgaris, which typically appears on the elbows, knees, scalp, and lower back. The exact cause is unknown, but it involves a combination of genetic, environmental, and immune system factors.

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    1. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment Gut · 2013 · 278 citations
    2. Role of regulatory T cells in psoriasis pathogenesis and treatment British Journal of Dermatology · 2020 · 273 citations
    3. Generalized Pustular Psoriasis Archives of Dermatology · 1991 · 143 citations
    4. Psoriasis of the Scalp American Journal of Clinical Dermatology · 2001 · 128 citations
    5. Animal Models of Psoriasis – What Can We Learn from Them? Journal of Investigative Dermatology · 1999 · 127 citations
    6. The histopathologic spectrum of psoriasis Clinics in Dermatology · 2007 · 111 citations
    7. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas Clinics in Dermatology · 2008 · 104 citations
    8. A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. Proceedings of the National Academy of Sciences · 1996 · 89 citations
    9. A review of acitretin, a systemic retinoid for the treatment of psoriasis Expert Opinion on Pharmacotherapy · 2005 · 75 citations
    10. Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia The American Journal of Dermatopathology · 2011 · 72 citations
    11. Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia? Journal of Investigative Dermatology · 2016 · 69 citations
    12. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    13. Concomitant Vitiligo and Psoriasis in a Patient Treated with Interferon Alfa‐2a for Chronic Hepatitis B Infection Pediatric Dermatology · 2004 · 60 citations
    14. Animal models of psoriasis—highlights and drawbacks 2020 · 53 citations
    15. Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis 2013 · 51 citations
    16. Metabolic syndrome and skin: Psoriasis and beyond Indian Journal of Dermatology · 2013 · 50 citations
    17. Autoimmunity and autoimmune co-morbidities in psoriasis Immunology · 2018 · 49 citations
    18. The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris Frontiers in Immunology · 2022 · 49 citations
    19. Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature Dermatology · 2012 · 49 citations
    20. Significance of the S100A4 Protein in Psoriasis Journal of Investigative Dermatology · 2009 · 45 citations
    21. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations
    22. Psoriatic alopecia Clinical and Experimental Dermatology · 2015 · 41 citations
    23. Treatment of Psoriasis vulgaris with a New Retinoic Acid Derivative Ro 10-9359 Dermatology · 1977 · 39 citations
    24. Turner's syndrome associated with psoriasis and alopecia areata Journal of the European Academy of Dermatology and Venereology · 2003 · 37 citations
    25. Metabolic Syndrome Prevalence in Psoriasis American Journal of Clinical Dermatology · 2014 · 32 citations
    26. Chemotherapy of psoriasis and other skin disorders with oral retinoids Pharmacology & Therapeutics · 1981 · 31 citations
    27. Recent advances in the treatment of psoriasis Journal of The American Academy of Dermatology · 1983 · 29 citations
    28. Psoriasis associated with vulval scarring Clinical and Experimental Dermatology · 2004 · 28 citations
    29. Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein Scientific Reports · 2018 · 27 citations
    30. Guidelines for the Use of Acitretin in Psoriasis Actas Dermo-Sifiliográficas · 2013 · 25 citations