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    Did you mean Prostaglandin D2 Receptor?
    Glossary Prostaglandin D2 Receptor

    protein on cell surfaces that binds prostaglandin D2, affecting hair growth

    The Prostaglandin D2 Receptor (often abbreviated as PTGDR or PTGDR2) is a protein found on the surface of certain cells that binds to prostaglandin D2, a type of lipid compound involved in various physiological processes. This receptor plays a significant role in inflammatory responses and has been linked to conditions like asthma and hair loss, particularly androgenetic alopecia, where its activation can inhibit hair growth.

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    1. Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (<i>Capra hircus</i>) Skin during Hair Follicle Development Animal Biotechnology · 2014 · 2 citations
    2. Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression Journal of Investigative Dermatology · 2019 · 2 citations
    3. Prostaglandin E <sub>2</sub> Receptor 2 Modulates Macrophage Activity for Cardiac Repair Journal of the American Heart Association · 2018 · 29 citations
    4. Recent Progress in Prostaglandin F 2a Ethanolamide (Prostamide F2a) Research and Therapeutics 2013 · 1 citations
    5. 850 After skin wounding, noncoding dsRNA coordinates prostaglandins and WNT7b to promote regeneration 2017
    6. 699 Effect of Prostaglandin D 2 on hair follicle growth and its impact on hair follicle stem/progenitor cells Journal of Investigative Dermatology · 2016 · 1 citations
    7. Characterization of Prostaglandin F<sub>2α</sub> Receptors in Human Eyelids European journal of ophthalmology · 2014 · 9 citations
    8. Cicatricial Alopecia Symposium 2011: Lipids, Inflammation and Stem Cells Journal of Investigative Dermatology · 2012 · 4 citations
    9. Hair Growth-Promoting Effects of a Multi-Targeted Cosmetic Formulation Containing PYGL, DP2, and 15-PGDH Inhibitors Developed Using AI-Based DeepZema® in Androgenetic Alopecia: A 24-Week Randomized Controlled Trial Cosmetics · 2026
    10. Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review International Journal of Molecular Sciences · 2022 · 10 citations
    11. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018 · 18 citations
    12. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44 Journal of Investigative Dermatology · 2012 · 68 citations
    13. Prostaglandin F2α stimulates the growth of human intermediate hair follicles in ex vivo organ culture with potential clinical relevance Frontiers in Physiology · 2025
    14. Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of prostaglandin F2α receptor activation Pharmacological Reports · 2026
    15. Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology International Journal of Molecular Sciences · 2025
    16. Recent Progress in Prostaglandin F<sub>2</sub><i><sub>α</sub></i>Ethanolamide (Prostamide F<sub>2</sub><i><sub>α</sub></i>) Research and Therapeutics Pharmacological reviews · 2013 · 43 citations
    17. Prostaglandin D2(PGD2); prostaglandin D2 receptor (CRTH2; GPR44; CD294); prostaglandin D2 synthase (PTGDS) Science-business Exchange · 2012 · 2 citations
    18. A new target for squamous cell skin cancer? Experimental Dermatology · 2014 · 6 citations
    19. Hypertrichosis around a leg ulcer being treated with prostaglandin E1 ointment Journal of the American Academy of Dermatology · 2011 · 3 citations
    20. Human Scalp Hair Follicles Express Prostaglandin E2 Lipid Mediator and Receptors For Pge2 2013
    21. HMGB1 promotes hair growth via the modulation of prostaglandin metabolism Scientific Reports · 2019 · 12 citations
    22. The physiological and pharmacological roles of prostaglandins in hair growth The Korean Journal of Physiology and Pharmacology · 2022
    23. 1017 The prostaglandin F2α analog bimatoprost activates secondary hair germ cells to promote hair growth through two distinct signaling pathways Journal of Investigative Dermatology · 2026
    24. Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2016
    25. Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    26. Madarosis, milphosis, eyelash trichomegaly, and dermatochalasis Clinics in Dermatology · 2015 · 10 citations
    27. Bad Hair Day: Testosterone and Wnts Journal of Investigative Dermatology · 2015 · 3 citations
    28. 702 dsRNA induces ectopic KRT9 expression via WNT/β-catenin-mediated signaling Journal of Investigative Dermatology · 2016
    29. Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a Journal of Dermatological Science · 2010 · 29 citations
    30. Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders Acta dermato-venereologica · 2017 · 16 citations