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The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Certain immune cells are more common on the top of the head and might help predict or treat common hair loss.

PGD2 stops hair growth and is higher in bald men with AGA.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Higher DHT in male baldness may protect against prostate cancer.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Higher levels of the DP2 receptor may lead to hair loss.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Androgens may block hair growth signals, targeting this could treat hair loss.

Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.

Prostanoids, like prostaglandins and thromboxane A2, can both enhance and inhibit hair growth, and understanding their effects could help treat hair disorders.

Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Men with a family history of hair loss on their mother's side are more likely to have female pattern hair loss.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.