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The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.

Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.

Burn scars heal abnormally and more research is needed to find better treatments.

The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

TLR4 is important in aging-related diseases and could be a new treatment target.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Hair gels may cause split ends in children.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Probiotics show promise for health benefits but need more research to understand how they work.

Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.

Lack of vitamin D might cause hair loss due to autoimmune problems, and fixing vitamin D levels could help treat it.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Certain IL-18 gene variations may increase the risk of alopecia areata.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Particulate matter causes inflammation in hair cells, potentially harming hair growth.

Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

17β-estradiol can reduce inflammation in the skin.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.