Search

everythinglearnresearchcommunity

for

Search:↓

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Testosterone is crucial for development, growth, and various body functions in mammals.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Finasteride reduces movement issues in Parkinson's disease rats.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Excess androgens may cause PCOS, not just be a symptom.