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This article discusses the mechanisms of hirsutism and acne in women, highlighting cyproterone acetate with ethinyloestradiol as an effective anti-androgen therapy in the UK, but it reports no new clinical findings.

This article reviews the use of spironolactone in dermatology for conditions like female acne, suggesting it may reduce antibiotic and isotretinoin use, and stresses its long-term safety.

This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.

This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.

This review discusses the pharmacological properties of progestins used in contraception and hormone replacement therapy, focusing on drospirenone's unique effects, but reports no new experimental findings.

This systematic review highlights the diverse uses and bioactivities of Impatiens plants, particularly their antimicrobial, cytotoxic, anti-inflammatory, anti-anaphylactic, and antioxidant properties, while noting the need for more research to validate their ethnobotanical applications and isolate major bioactive compounds.

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

This article reviews the scientific exploration of Ayurvedic medicinal plants and discusses their modern applications, such as a drug developed from Commiphora wightti for lipid disorders, without reporting new clinical findings.

This review explores various substances with potential antiandrogenic effects for treating acne, highlighting evidence for isotretinoin, and discusses the future consideration of 5 alpha-reductase inhibitors as antiandrogens.

This article reviews the role of androgens and oral contraceptives in acne pathogenesis and management but presents no new clinical results.

This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.

This study suggests that weight loss can improve fertility outcomes in overweight and obese women with PCOS, and letrozole should be considered the new first-line treatment over clomiphene citrate for anovulatory infertility in this population.

This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.

This review evaluates the literature on the ethnopharmacology, phytochemistry, and therapeutic potential of Darmana Turki (Artemisia maritima L.) and reports no new clinical findings.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.

In this study, iontophoresis of medroxyprogesterone acetate significantly reduced hair growth rate in women with idiopathic facial hirsutism, without affecting serum androgen levels, and was well-tolerated as a treatment option.

This study found that combining cyproterone acetate with testosterone enanthate was highly effective in suppressing spermatogenesis, suggesting potential as a reversible male contraceptive method.

This review discusses the use of antiandrogens for various conditions like prostate cancer and highlights their potential benefits in remission rates and symptom improvement, but it reports no new clinical results.

This study found that combining flutamide with an oral contraceptive significantly reduced hirsutism, acne, and seborrhea in patients after seven months, without significant side effects.

This report describes a case of meningioma in a transwoman treated long-term with estradiol and cyproterone acetate, suggesting possible concern over female sex steroids and meningioma risk.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.

In this study, a treatment regimen combining cyproterone acetate and ethinyl estradiol significantly improved acne and seborrhoea in most women after three months, but had varied effects on hirsutism and alopecia.

This study found that flutamide was more effective than spironolactone in reducing symptoms of hirsutism and related conditions in premenopausal women, with fewer discontinuations due to side effects.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

This study found that the progestins norgestimate and dienogest may help treat clinical hyperandrogeny in women by inhibiting skin 5 alpha-reductase activity with minimal androgenic potential.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

This study found that sebaceous glands in bald scalp have greater androgen binding affinity and capacity than those in hairy scalp, possibly contributing to the androgenic response seen in male pattern baldness.