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    Did you mean Primary Hair Follicles?
    Glossary Primary Hair Follicles

    initial hair-producing structures formed during fetal development

    Primary hair follicles are the initial hair-producing structures that develop in the skin during fetal development. These follicles typically give rise to thicker, coarser hairs, such as those found on the scalp, eyebrows, and eyelashes. They are distinct from secondary hair follicles, which produce finer, shorter hairs like those on the body and face.

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    1. Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018 · 37 citations
    2. Comparative Transcriptome Analysis Reveals that a Ubiquitin-Mediated Proteolysis Pathway Is Important for Primary and Secondary Hair Follicle Development in Cashmere Goats PLoS ONE · 2016 · 31 citations
    3. Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats BMC veterinary research · 2022 · 2 citations
    4. A 4kb Fragment of the Desmocollin 3 Promoter Directs Reporter Gene Expression to Parakeratotic Epidermis and Primary Hair Follicles Journal of Investigative Dermatology · 2006 · 1 citations
    5. Effects of Estradiol on Culture in vitro of Cashmere Goat Primary Hair Follicles Anhui nongye kexue · 2009
    6. Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2025
    7. Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia? Clinical and Experimental Dermatology · 2009 · 39 citations
    8. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021 · 16 citations
    9. Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells Frontiers in Cellular and Infection Microbiology · 2018 · 14 citations
    10. Transient treatment of pregnant Merino ewes with modulators of cortisol biosynthesis coinciding with primary wool follicle initiation alters lifetime wool growth Animal Production Science · 2013 · 7 citations
    11. [Primary observation on construction of skin with human hair follicle bulge cells with tissue engineering technique]. PubMed · 2007 · 4 citations
    12. 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts Journal of Investigative Dermatology · 2020
    13. HAIR FOLLICLE STEM CELLS IN THE PATHOGENESIS OF PRIMARY CICATRICIAL ALOPECIA Zagazig University Medical Journal · 2015
    14. Unusual Clinical Presentation of a Primary Cutaneous Follicle Center Lymphoma on the Scalp of a Middle-Aged Female: Case Report and Review of the Literature Skin appendage disorders · 2019 · 3 citations
    15. Atypical clinical presentation of primary and secondary cutaneous follicle center lymphoma (FCL) on the head characterized by macular lesions Journal of The American Academy of Dermatology · 2016 · 18 citations
    16. Primary cutaneous follicle center lymphoma presenting as frontal fibrosing alopecia Dermatology Online Journal · 2025
    17. Primary cutaneous follicle centre cell lymphoma of the scalp presenting with scarring alopecia British Journal of Dermatology · 2011 · 13 citations
    18. Extracellular vesicles released by hair follicle and adipose mesenchymal stromal cells induce comparable neuroprotective and anti-inflammatory effects in primary neuronal and microglial cultures Cytotherapy · 2023
    19. Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro European Journal of Cell Biology · 2010 · 42 citations
    20. The cause of primary and secondary damage to hair follicles on full thickness skin autografts Archives of Dermatological Research · 1974 · 2 citations
    21. Influences of IGF-1 and EGF on primary hair follicles of Liaoning cashmere goat in vitro. Shenyang Nongye Daxue xuebao · 2010 · 1 citations
    22. Effects of Estradiol on Cashmere Goat Primary Hair Follicles Cultured in vitro 农业科学与技术(英文版) · 2008
    23. Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus) PLoS ONE · 2013 · 81 citations
    24. Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia Cell & Bioscience · 2025
    25. 85 Primary cutaneous follicle center lymphoma spans yet unrecognised subtypes including polyclonal reactions Journal of Investigative Dermatology · 2025
    26. Nonviral in Situ Green Fluorescent Protein Labeling and Culture of Primary, Adult Human Hair Follicle Epithelial Progenitor Cells Stem Cells · 2009 · 43 citations
    27. Corrigendum to “Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro” [Eur. J. Cell Biol. (2010) 769–777] European Journal of Cell Biology · 2012 · 1 citations
    28. 726 The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning Journal of Investigative Dermatology · 2022
    29. 318 The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning Journal of Investigative Dermatology · 2021
    30. LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth Development · 2016 · 43 citations